Reactome | BRD7:p-S15,S20-TP53:EP300 [nucleoplasm]

Schema > Complex > Entries

BRD7:p-S15,S20-TP53:EP300 [nucleoplasm] Show undefined attributes

candidateOf	[CandidateSet:R-HSA-6805649] KAT6A:ING5:MEAF6:BRPF1,(2,3):PML:Ac-K120,p-S15,S20-TP53, BRD7:p-S15,S20-TP53:EP300 [nucleoplasm] - Homo sapiens
catalystActivities	[CatalystActivity:5628869] acetyltransferase activity of BRD7:p-S15,S20-TP53:EP300 [nucleoplasm]
compartment	[Compartment:7660] nucleoplasm
consumedByEvent	[Reaction:R-HSA-5628871] BRD7 promotes EP300-mediated acetylation of TP53 - Homo sapiens
created	[InstanceEdit:3222106] Orlic-Milacic, M, 2013-03-18
dbId	3222096
displayName	BRD7:p-S15,S20-TP53:EP300 [nucleoplasm]
hasComponent	[EntityWithAccessionedSequence:R-HSA-3222092] BRD7 [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-381325] EP300 [nucleoplasm] [Complex:R-HSA-3222171] p-S15,S20-TP53 Tetramer [nucleoplasm]
inDisease	false
inferredTo	[Complex:R-MMU-3222096] BRD7:p-S15,S20-TP53:EP300 [nucleoplasm] - Mus musculus [Complex:R-RNO-3222096] BRD7:p-S15,S20-TP53:EP300 [nucleoplasm] - Rattus norvegicus [Complex:R-CFA-3222096] BRD7:p-S15,S20-TP53:EP300 [nucleoplasm] - Canis familiaris [Complex:R-BTA-3222096] BRD7:p-S15,S20-TP53:EP300 [nucleoplasm] - Bos taurus [Complex:R-SSC-3222096] BRD7:p-S15,S20-TP53:EP300 [nucleoplasm] - Sus scrofa [Complex:R-XTR-3222096] BRD7:p-S15,S20-TP53:EP300 [nucleoplasm] - Xenopus tropicalis [Complex:R-DME-3222096] BRD7:p-S15,S20-TP53:EP300 [nucleoplasm] - Drosophila melanogaster
isChimeric	false
literatureReference	[LiteratureReference:3222107] BRD7 is a candidate tumour suppressor gene required for p53 function [LiteratureReference:3222101] Polybromo-associated BRG1-associated factor components BRD7 and BAF180 are critical regulators of p53 required for induction of replicative senescence
maxDepth	3
modified	[InstanceEdit:6805632] Orlic-Milacic, Marija, 2015-10-20
name	BRD7:p-S15,S20-TP53:EP300
producedByEvent	[Reaction:R-HSA-3222093] BRD7 binds TP53 and EP300 - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-3222096

Referrals

(hasCandidate)	[CandidateSet:R-HSA-6805649] KAT6A:ING5:MEAF6:BRPF1,(2,3):PML:Ac-K120,p-S15,S20-TP53, BRD7:p-S15,S20-TP53:EP300 [nucleoplasm]
(output)	[Reaction:R-HSA-3222093] BRD7 binds TP53 and EP300
(input)	[Reaction:R-HSA-5628871] BRD7 promotes EP300-mediated acetylation of TP53
(physicalEntity)	[CatalystActivity:5628869] acetyltransferase activity of BRD7:p-S15,S20-TP53:EP300 [nucleoplasm]

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