Reactome | SNAP25(1-197) [plasma membrane]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:3004547] Jassal, Bijay, 2013-01-29
crossReference	[DatabaseIdentifier:12020820] Mondo:0005498
dbId	3004546
disease	[Disease:3632909] botulism
displayName	SNAP25(1-197) [plasma membrane]
endCoordinate	197
hasModifiedResidue	[ModifiedResidue:5244496] S-palmitoyl-L-cysteine at 85 [ModifiedResidue:5244508] S-palmitoyl-L-cysteine at 88 [ModifiedResidue:5244495] S-palmitoyl-L-cysteine at 90 [ModifiedResidue:5244510] S-palmitoyl-L-cysteine at 92
inDisease	true
literatureReference	[LiteratureReference:181730] Proteolysis of SNAP-25 by types E and A botulinal neurotoxins [LiteratureReference:181774] Proteolysis of SNAP-25 isoforms by botulinum neurotoxin types A, C, and E: domains and amino acid residues controlling the formation of enzyme-substrate complexes and cleavage
maxDepth	1
modified	[InstanceEdit:5244505] D'Eustachio, Peter, 2014-01-18
name	SNAP25(1-197) Synaptosomal-associated protein 25, residues 1-197
producedByEvent	[Reaction:R-HSA-194818] botA LC cleaves target cell SNAP25 - Homo sapiens
referenceEntity	[ReferenceGeneProduct:uniprot:P60880] UniProt:P60880 SNAP25
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-3004546
startCoordinate	1
updateTrackers	[UpdateTracker:9889044] Update Tracker - [EntityWithAccessionedSequence:3004546] SNAP25(1-197) [plasma membrane] - v48:[addDisease, addHasModifiedResidue, addLiteratureReference, modifyName]

(updatedInstance)	[UpdateTracker:9889044] Update Tracker - [EntityWithAccessionedSequence:3004546] SNAP25(1-197) [plasma membrane] - v48:[addDisease, addHasModifiedResidue, addLiteratureReference, modifyName]
(output)	[Reaction:R-HSA-194818] botA LC cleaves target cell SNAP25

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