Reactome | p-8S,3T-BORA:SCF-beta-TrCp1/2 [cytosol]

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p-8S,3T-BORA:SCF-beta-TrCp1/2 [cytosol] Show undefined attributes

catalystActivities	[CatalystActivity:3000336] ubiquitin-protein transferase activity of p-8S,3T-BORA:SCF-beta-TrCp1/2 [cytosol]
compartment	[Compartment:70101] cytosol
consumedByEvent	[Reaction:R-HSA-3000335] SCF-beta-TrCp1/2 ubiquitinates phosphorylated BORA - Homo sapiens
created	[InstanceEdit:3000338] Orlic-Milacic, M, 2013-01-24
dbId	3000340
displayName	p-8S,3T-BORA:SCF-beta-TrCp1/2 [cytosol]
hasComponent	[DefinedSet:R-HSA-1168601] (BTRC:CUL1:SKP1),(FBXW11:CUL1:SKP1) [cytosol] [EntityWithAccessionedSequence:R-HSA-3000330] p-8S,3T-BORA [cytosol]
inDisease	false
inferredTo	[Complex:R-MMU-3000340] p-8S,3T-BORA:SCF-beta-TrCp1/2 [cytosol] - Mus musculus [Complex:R-RNO-3000340] p-8S,3T-BORA:SCF-beta-TrCp1/2 [cytosol] - Rattus norvegicus [Complex:R-CFA-3000340] p-8S,3T-BORA:SCF-beta-TrCp1/2 [cytosol] - Canis familiaris [Complex:R-BTA-3000340] p-8S,3T-BORA:SCF-beta-TrCp1/2 [cytosol] - Bos taurus [Complex:R-DRE-3000340] p-8S,3T-BORA:SCF-beta-TrCp1/2 [cytosol] - Danio rerio [Complex:R-XTR-3000340] p-8S,3T-BORA:SCF-beta-TrCp1/2 [cytosol] - Xenopus tropicalis [Complex:R-GGA-3000340] p-8S,3T-BORA:SCF-beta-TrCp1/2 [cytosol] - Gallus gallus [Complex:R-DME-3000340] p-8S,3T-BORA:SCF-beta-TrCp1/2 [cytosol] - Drosophila melanogaster [Complex:R-CEL-3000340] p-8S,3T-BORA:SCF-beta-TrCp1/2 [cytosol] - Caenorhabditis elegans [Complex:R-DDI-3000340] p-8S,3T-BORA:SCF-beta-TrCp1/2 [cytosol] - Dictyostelium discoideum [Complex:R-SPO-3000340] p-8S,3T-BORA:SCF-beta-TrCp1/2 [cytosol] - Schizosaccharomyces pombe [Complex:R-SCE-3000340] p-8S,3T-BORA:SCF-beta-TrCp1/2 [cytosol] - Saccharomyces cerevisiae [Complex:R-PFA-3000340] p-8S,3T-BORA:SCF-beta-TrCp1/2 [cytosol] - Plasmodium falciparum
isChimeric	false
literatureReference	[LiteratureReference:3000332] Plk1- and beta-TrCP-dependent degradation of Bora controls mitotic progression
maxDepth	4
modified	[InstanceEdit:9929897] Orlic-Milacic, Marija, 2024-11-29
name	p-8S,3T-BORA:SCF-beta-TrCp1/2
producedByEvent	[Reaction:R-HSA-3000339] Phosphorylated BORA binds SCF-beta-TrCp1/2 - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-3000340
updateTrackers	[UpdateTracker:9939880] Update Tracker - [Complex:3000340] p-8S,3T-BORA:SCF-beta-TrCp1/2 [cytosol] - v92:[modifyName] [UpdateTracker:9896141] Update Tracker - [Complex:3000340] p-S252,S497,T501-BORA:SCF-beta-TrCp1/2 [cytosol] - v60:[updateContainedComponent] [UpdateTracker:9889365] Update Tracker - [Complex:3000340] p-S252,S497,T501-BORA:SCF-beta-TrCp1/2 [cytosol] - v48:[updateContainedComponent]

Referrals

(updatedInstance)	[UpdateTracker:9939880] Update Tracker - [Complex:3000340] p-8S,3T-BORA:SCF-beta-TrCp1/2 [cytosol] - v92:[modifyName] [UpdateTracker:9896141] Update Tracker - [Complex:3000340] p-S252,S497,T501-BORA:SCF-beta-TrCp1/2 [cytosol] - v60:[updateContainedComponent] [UpdateTracker:9889365] Update Tracker - [Complex:3000340] p-S252,S497,T501-BORA:SCF-beta-TrCp1/2 [cytosol] - v48:[updateContainedComponent]
(output)	[Reaction:R-HSA-3000339] Phosphorylated BORA binds SCF-beta-TrCp1/2
(input)	[Reaction:R-HSA-3000335] SCF-beta-TrCp1/2 ubiquitinates phosphorylated BORA
(physicalEntity)	[CatalystActivity:3000336] ubiquitin-protein transferase activity of p-8S,3T-BORA:SCF-beta-TrCp1/2 [cytosol]

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