Reactome | Conjugation of SUMO3 to UBA2:SAE1

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Conjugation of SUMO3 to UBA2:SAE1 Show undefined attributes

authored	[InstanceEdit:2984266] May, B, 2013-01-16
catalystActivity	[CatalystActivity:2993766] SUMO activating enzyme activity of UBA2:SAE1 [nucleoplasm]
category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:2993794] May, B, 2013-01-19
dbId	2993781
displayName	Conjugation of SUMO3 to UBA2:SAE1
edited	[InstanceEdit:2984266] May, B, 2013-01-16
eventOf	[Pathway:R-HSA-3065676] SUMO is conjugated to E1 (UBA2:SAE1) - Homo sapiens
followingEvent	[Reaction:R-HSA-2993769] Transfer of SUMO3 from E1 to UBE2I (UBC9) - Homo sapiens
inferredFrom	[Reaction:R-HSA-2990833] Conjugation of SUMO1 to UBA2:SAE1 - Homo sapiens
input	[SimpleEntity:R-ALL-29358] ATP [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-2984269] SUMO3 [nucleoplasm] [Complex:R-HSA-2990843] UBA2:SAE1 [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	true
literatureReference	[LiteratureReference:3214967] Performing in vitro sumoylation reactions using recombinant enzymes [LiteratureReference:3215023] Polymeric chains of SUMO-2 and SUMO-3 are conjugated to protein substrates by SAE1/SAE2 and Ubc9
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Conjugation of SUMO3 to UBA2:SAE1
output	[SimpleEntity:R-ALL-164121] AMP [nucleoplasm] [SimpleEntity:R-ALL-113541] PPi [nucleoplasm] [Complex:R-HSA-2993762] SUMO3:UBA2:SAE1 [nucleoplasm]
precedingEvent	[Reaction:R-HSA-2993763] SENP1,2,5 proteolytically process SUMO3 - Homo sapiens
releaseDate	2013-06-11
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:3448698] Garg, Amit K, 2013-05-16
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-2993781
summation	[Summation:3222559] The UBA2:SAE1 complex catalyzes the formation of a thioester...

Referrals

(hasEvent)	[Pathway:R-HSA-3065676] SUMO is conjugated to E1 (UBA2:SAE1)
(precedingEvent)	[Reaction:R-HSA-2993769] Transfer of SUMO3 from E1 to UBE2I (UBC9)
(inferredTo)	[Reaction:R-HSA-2990833] Conjugation of SUMO1 to UBA2:SAE1

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