Reactome | CIA Targeting Complex transfers 4Fe-4S cluster to apoproteins

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CIA Targeting Complex transfers 4Fe-4S cluster to apoproteins Show undefined attributes

authored	[InstanceEdit:2564829] Lill, Roland, 2012-11-07
catalystActivity	[CatalystActivity:8855869] iron-sulfur transferase activity of NARFL:CIAO1:FAM96B:MMS19 [cytosol]
catalystActivityReference	[CatalystActivityReference:9643323] iron-sulfur transferase activity of NARFL:CIAO1:FAM96B:MMS19 [cytosol] MMS19 assembles iron-sulfur proteins required for DNA metabolism and genomic integrity
category	omitted
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:2564823] May, B, 2012-11-07
dbId	2564828
displayName	CIA Targeting Complex transfers 4Fe-4S cluster to apoproteins
edited	[InstanceEdit:2564820] May, B, 2012-11-07
eventOf	[Pathway:R-HSA-2564830] Cytosolic iron-sulfur cluster assembly - Homo sapiens
inferredFrom	[BlackBoxEvent:R-SCE-2564817] CIA Targeting Complex transfers 4Fe-4S clusters to apoproteins - Saccharomyces cerevisiae
input	[DefinedSet:R-HSA-2564793] Apoprotein Lacking 4Fe-4S Cluster [cytosol] [Complex:R-HSA-2564798] NUBP2:4Fe-4S:NUBP1 [cytosol]
isChimeric	false
isInDisease	false
isInferred	true
literatureReference	[LiteratureReference:2564748] MMS19 assembles iron-sulfur proteins required for DNA metabolism and genomic integrity [LiteratureReference:2564719] MMS19 links cytoplasmic iron-sulfur cluster assembly to DNA metabolism [LiteratureReference:2976524] The Mammalian Proteins MMS19, MIP18, and ANT2 Are Involved in Cytoplasmic Iron-Sulfur Cluster Protein Assembly
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	CIA Targeting Complex transfers 4Fe-4S cluster to apoproteins
output	[DefinedSet:R-HSA-2564791] Holoprotein Containing 4Fe-4S Cluster [cytosol] 2 × [Complex:R-HSA-2564799] NUBP1:4Fe-4S [cytosol] 2 × [EntityWithAccessionedSequence:R-HSA-2564767] NUBP2 [cytosol]
precedingEvent	[BlackBoxEvent:R-HSA-2564826] 4Fe-4S cluster assembles on NUBP2:NUBP1 scaffold - Homo sapiens
releaseDate	2013-03-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:3018411] Uringa, Evert-Jan, 2013-02-05
schemaClass	BlackBoxEvent
species	[Species:48887] Homo sapiens
stId	R-HSA-2564828
summation	[Summation:2564704] A complex of four proteins termed CIA targeting complex is i...
updateTrackers	[UpdateTracker:9783421] Update Tracker - [BlackBoxEvent:2564828] CIA Targeting Complex transfers 4Fe-4S cluster to apoproteins - v56:[addCatalystActivity, removeInput, removeOutput]

Referrals

(updatedInstance)	[UpdateTracker:9783421] Update Tracker - [BlackBoxEvent:2564828] CIA Targeting Complex transfers 4Fe-4S cluster to apoproteins - v56:[addCatalystActivity, removeInput, removeOutput]
(hasEvent)	[Pathway:R-HSA-2564830] Cytosolic iron-sulfur cluster assembly
(inferredTo)	[BlackBoxEvent:R-SCE-2564817] CIA Targeting Complex transfers 4Fe-4S clusters to apoproteins

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