Reactome | SCARB1:Endocytosed Ligand [plasma membrane]

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SCARB1:Endocytosed Ligand [plasma membrane] Show undefined attributes

compartment	[Compartment:876] plasma membrane
consumedByEvent	[BlackBoxEvent:R-HSA-2512800] SCARB1:ligand is endocytosed - Homo sapiens
created	[InstanceEdit:2512796] May, B, 2012-10-07
dbId	2512792
displayName	SCARB1:Endocytosed Ligand [plasma membrane]
hasComponent	[DefinedSet:R-HSA-2512795] Endocytosed Ligands of SCARB1 [extracellular region] [EntityWithAccessionedSequence:R-HSA-349415] SCARB1-2 [plasma membrane]
inDisease	false
includedLocation	[Compartment:984] extracellular region
inferredTo	[Complex:R-MMU-2512792] SCARB1:Endocytosed Ligand [plasma membrane] - Mus musculus [Complex:R-RNO-2512792] SCARB1:Endocytosed Ligand [plasma membrane] - Rattus norvegicus [Complex:R-CFA-2512792] SCARB1:Endocytosed Ligand [plasma membrane] - Canis familiaris [Complex:R-BTA-2512792] SCARB1:Endocytosed Ligand [plasma membrane] - Bos taurus [Complex:R-SSC-2512792] SCARB1:Endocytosed Ligand [plasma membrane] - Sus scrofa [Complex:R-GGA-2512792] SCARB1:Endocytosed Ligand [plasma membrane] - Gallus gallus
isChimeric	false
literatureReference	[LiteratureReference:2197601] CLA-1 is an 85-kD plasma membrane glycoprotein that acts as a high-affinity receptor for both native (HDL, LDL, and VLDL) and modified (OxLDL and AcLDL) lipoproteins [LiteratureReference:2197623] Uptake and fate of class B scavenger receptor ligands in HepG2 cells [LiteratureReference:2197596] Serum amyloid A binding to CLA-1 (CD36 and LIMPII analogous-1) mediates serum amyloid A protein-induced activation of ERK1/2 and p38 mitogen-activated protein kinases [LiteratureReference:2197628] Binding and internalization of lipopolysaccharide by Cla-1, a human orthologue of rodent scavenger receptor B1 [LiteratureReference:349651] Characterization of CLA-1, a human homologue of rodent scavenger receptor BI, as a receptor for high density lipoprotein and apoptotic thymocytes
maxDepth	4
name	SCARB1:Endocytosed Ligand SR-BI:Endocytosed Ligand
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-2512792

Referrals

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[BlackBoxEvent:R-HSA-2512800] SCARB1:ligand is endocytosed

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