Reactome | Requirement by 'Mg2+ [nucleoplasm]'

Schema > Requirement > Entries

created	[InstanceEdit:2509820] D'Eustachio, P, 2012-10-05
dbId	2509822
displayName	Requirement by 'Mg2+ [nucleoplasm]'
modified	[InstanceEdit:9608020] Wu, G, 2018-05-08
regulatedEntity	[Reaction:R-XTR-2509816] NUDT16 hydrolyses IDP to IMP - Xenopus tropicalis [Reaction:R-SSC-2509816] NUDT16 hydrolyses IDP to IMP - Sus scrofa [Reaction:R-BTA-2509816] NUDT16 hydrolyses IDP to IMP - Bos taurus [Reaction:R-HSA-2509816] NUDT16 hydrolyses IDP to IMP - Homo sapiens [Reaction:R-XTR-2509793] NUDT16 hydrolyses dIDP to dIMP - Xenopus tropicalis [Reaction:R-SSC-2509793] NUDT16 hydrolyses dIDP to dIMP - Sus scrofa [Reaction:R-BTA-2509793] NUDT16 hydrolyses dIDP to dIMP - Bos taurus
regulator	[SimpleEntity:R-ALL-2509819] Mg2+ [nucleoplasm]
schemaClass	Requirement
stId	R-HSA-2509822

(regulatedBy)	[Reaction:R-XTR-2509816] NUDT16 hydrolyses IDP to IMP [Reaction:R-SSC-2509816] NUDT16 hydrolyses IDP to IMP [Reaction:R-BTA-2509816] NUDT16 hydrolyses IDP to IMP [Reaction:R-HSA-2509816] NUDT16 hydrolyses IDP to IMP [Reaction:R-XTR-2509793] NUDT16 hydrolyses dIDP to dIMP [Reaction:R-SSC-2509793] NUDT16 hydrolyses dIDP to dIMP [Reaction:R-BTA-2509793] NUDT16 hydrolyses dIDP to dIMP
(regulation)	[RegulationReference:9641681] Requirement by 'Mg2+ [nucleoplasm]' NUDT16 is a (deoxy)inosine diphosphatase, and its deficiency induces accumulation of single-strand breaks in nuclear DNA and growth arrest

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