Reactome | 11cRAL binds to opsin to form 11c-retinyl:RHO

Schema > Reaction > Entries

11cRAL binds to opsin to form 11c-retinyl:RHO Show undefined attributes

authored	[InstanceEdit:2454115] Jassal, Bijay, 2012-08-21
category	transition
compartment	[Compartment:70101] cytosol [Compartment:74000] photoreceptor outer segment membrane
created	[InstanceEdit:2454115] Jassal, Bijay, 2012-08-21
dbId	2454118
displayName	11cRAL binds to opsin to form 11c-retinyl:RHO
edited	[InstanceEdit:2454115] Jassal, Bijay, 2012-08-21
eventOf	[Pathway:R-HSA-2453902] The canonical retinoid cycle in rods (twilight vision) - Homo sapiens
followingEvent	[Reaction:R-HSA-74101] Photons induce isomerization of 11c-retinyl to at-retinyl - Homo sapiens
input	[SimpleEntity:R-ALL-32737] 11cRAL [cytosol] [EntityWithAccessionedSequence:R-HSA-419802] RHO [photoreceptor disc membrane]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:74327] Isolation and nucleotide sequence of the gene encoding human rhodopsin. [LiteratureReference:2454267] Localization of the retinal protonated Schiff base counterion in rhodopsin [LiteratureReference:2454273] Rhodopsin with 11-cis-locked chromophore is capable of forming an active state photoproduct
maxDepth	1
modified	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
name	11cRAL binds to opsin to form 11c-retinyl:RHO 11-cis-retinal binds to rhodopsin
orthologousEvent	[Reaction:R-GGA-2454118] 11cRAL binds to opsin to form 11c-retinyl:RHO - Gallus gallus [Reaction:R-XTR-2454118] 11cRAL binds to opsin to form 11c-retinyl:RHO - Xenopus tropicalis [Reaction:R-DRE-2454118] 11cRAL binds to opsin to form 11c-retinyl:RHO - Danio rerio [Reaction:R-SSC-2454118] 11cRAL binds to opsin to form 11c-retinyl:RHO - Sus scrofa [Reaction:R-BTA-2454118] 11cRAL binds to opsin to form 11c-retinyl:RHO - Bos taurus [Reaction:R-CFA-2454118] 11cRAL binds to opsin to form 11c-retinyl:RHO - Canis familiaris [Reaction:R-RNO-2454118] 11cRAL binds to opsin to form 11c-retinyl:RHO - Rattus norvegicus [Reaction:R-MMU-2454118] 11cRAL binds to opsin to form 11c-retinyl:RHO - Mus musculus
output	[EntityWithAccessionedSequence:R-HSA-5205900] 11c-retinyl-RHO [photoreceptor disc membrane] [SimpleEntity:R-ALL-29356] H2O [cytosol]
precedingEvent	[BlackBoxEvent:R-HSA-2454113] RBP3 transports 11cRAL to rod photoreceptor outer segment - Homo sapiens [Reaction:R-HSA-74948] PP2A dephosphorylates p-RHO to RHO - Homo sapiens
releaseDate	2013-03-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:3006584] Blaner, William S, 2013-01-31
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-2454118
summation	[Summation:2454116] Human opsin-2 is a G-protein coupled photoreceptor found in ...
updateTrackers	[UpdateTracker:9786774] Update Tracker - [Reaction:2454118] 11cRAL binds to opsin to form 11c-retinyl:RHO - v48:[add_removeOutput, modifyText]

Referrals

(updatedInstance)	[UpdateTracker:9786774] Update Tracker - [Reaction:2454118] 11cRAL binds to opsin to form 11c-retinyl:RHO - v48:[add_removeOutput, modifyText]
(hasEvent)	[Pathway:R-HSA-2453902] The canonical retinoid cycle in rods (twilight vision)
(precedingEvent)	[Reaction:R-HSA-74101] Photons induce isomerization of 11c-retinyl to at-retinyl