Reactome | RBP4 binds atROL

Schema > Reaction > Entries

RBP4 binds atROL Show undefined attributes

authored	[InstanceEdit:2404143] Jassal, B, 2012-07-16
catalystActivity	[CatalystActivity:9960210] all-trans-retinol binding activity of RBP4(19-201) [extracellular region]
category	transition
compartment	[Compartment:984] extracellular region
created	[InstanceEdit:2404143] Jassal, B, 2012-07-16
dbId	2404135
diseaseReaction	[FailedReaction:R-HSA-2466828] Defective RBP4 does not bind atROL - Homo sapiens
displayName	RBP4 binds atROL
edited	[InstanceEdit:2404143] Jassal, B, 2012-07-16
eventOf	[Pathway:R-HSA-975634] Retinoid metabolism and transport - Homo sapiens
followingEvent	[Reaction:R-HSA-2404134] RBP4:atROL binds TTR - Homo sapiens
input	[SimpleEntity:R-ALL-2395761] atROL [extracellular region] [EntityWithAccessionedSequence:R-HSA-2453675] RBP4(19-201) [extracellular region]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:2453693] Retinol-binding protein: the transport protein for vitamin A in human plasma [LiteratureReference:2453714] Phenotype in retinol deficiency due to a hereditary defect in retinol binding protein synthesis
maxDepth	1
modified	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
name	RBP4 binds atROL
orthologousEvent	[Reaction:R-CEL-2404135] RBP4 binds atROL - Caenorhabditis elegans [Reaction:R-GGA-2404135] RBP4 binds atROL - Gallus gallus [Reaction:R-XTR-2404135] RBP4 binds atROL - Xenopus tropicalis [Reaction:R-DRE-2404135] RBP4 binds atROL - Danio rerio [Reaction:R-SSC-2404135] RBP4 binds atROL - Sus scrofa [Reaction:R-BTA-2404135] RBP4 binds atROL - Bos taurus [Reaction:R-CFA-2404135] RBP4 binds atROL - Canis familiaris [Reaction:R-RNO-2404135] RBP4 binds atROL - Rattus norvegicus [Reaction:R-MMU-2404135] RBP4 binds atROL - Mus musculus
output	[Complex:R-HSA-2453678] RBP4:atROL [extracellular region]
precedingEvent	[BlackBoxEvent:R-HSA-2404139] HSC cytosolic atROL translocates to extracellular region - Homo sapiens
previousReviewStatus	[ReviewStatus:9821385] four stars
releaseDate	2013-03-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:3006584] Blaner, William S, 2013-01-31 [InstanceEdit:9963238] Hill, David P, 2025-08-13
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-2404135
summation	[Summation:2453668] At the stellate cell surface, all-trans-retinol (atROL) bind...
updateTrackers	[UpdateTracker:9964734] Update Tracker - [Reaction:2404135] RBP4 binds atROL - v94:[removeCatalystActivity]

Referrals

(updatedInstance)	[UpdateTracker:9964734] Update Tracker - [Reaction:2404135] RBP4 binds atROL - v94:[removeCatalystActivity]
(hasEvent)	[Pathway:R-HSA-975634] Retinoid metabolism and transport
(precedingEvent)	[Reaction:R-HSA-2404134] RBP4:atROL binds TTR
(normalReaction)	[FailedReaction:R-HSA-2466828] Defective RBP4 does not bind atROL