Reactome | PTEN R233* [cytosol]

Schema > EntityWithAccessionedSequence > Entries

candidateOf	[CandidateSet:R-HSA-2318581] PTEN Truncation Mutants [cytosol] - Homo sapiens
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:2318575] Orlic-Milacic, M, 2012-06-13
crossReference	[DatabaseIdentifier:12021333] Mondo:0005509 [DatabaseIdentifier:2318580] COSMIC:COSV64288653 [DatabaseIdentifier:2318579] COSMIC:COSM21343
dbId	2318573
disease	[Disease:1500689] cancer [Disease:2317358] endometrial cancer [Disease:2317476] acute lymphocytic leukemia [Disease:1248674] large intestine cancer [Disease:1614672] cervical cancer [Disease:1500699] lung cancer [Disease:2317423] histiocytoma [Disease:1996312] brain glioma [Disease:1247632] glioblastoma [Disease:2317371] ovarian endometrioid neoplasm
displayName	PTEN R233* [cytosol]
endCoordinate	232
hasModifiedResidue	[NonsenseMutation:5640163] Nonsense mutation at L-arginine 233
inDisease	true
maxDepth	1
modified	[InstanceEdit:9967512] D'Eustachio, Peter, 2025-09-30
name	PTEN R233* PTEN Arg233*
referenceEntity	[ReferenceGeneProduct:uniprot:P60484] UniProt:P60484 PTEN
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-2318573
startCoordinate	2
updateTrackers	[UpdateTracker:9972743] Update Tracker - [EntityWithAccessionedSequence:2318573] PTEN R233* [cytosol] - v95:[modifyStartCoordinate] [UpdateTracker:9888511] Update Tracker - [EntityWithAccessionedSequence:2318573] PTEN R233* [cytosol] - v46:[modifyName]

(updatedInstance)	[UpdateTracker:9972743] Update Tracker - [EntityWithAccessionedSequence:2318573] PTEN R233* [cytosol] - v95:[modifyStartCoordinate] [UpdateTracker:9888511] Update Tracker - [EntityWithAccessionedSequence:2318573] PTEN R233* [cytosol] - v46:[modifyName]
(hasCandidate)	[CandidateSet:R-HSA-2318581] PTEN Truncation Mutants [cytosol]

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