Reactome | p-S-AKT:PIP3 [plasma membrane]

Schema > Complex > Entries

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-HSA-2317313] p-S-AKT:PDPK1:PIP3 [plasma membrane] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-2317314] AKT binds PDPK1 - Homo sapiens
created	[InstanceEdit:2317311] Orlic-Milacic, M, 2012-06-09
dbId	2317310
displayName	p-S-AKT:PIP3 [plasma membrane]
hasComponent	[CandidateSet:R-HSA-2317317] p-S-AKT [plasma membrane] [SimpleEntity:R-ALL-179838] PI(3,4,5)P3 [plasma membrane]
inDisease	false
inferredTo	[Complex:R-MMU-2317310] p-S-AKT:PIP3 [plasma membrane] - Mus musculus [Complex:R-RNO-2317310] p-S-AKT:PIP3 [plasma membrane] - Rattus norvegicus [Complex:R-DRE-2317310] p-S-AKT:PIP3 [plasma membrane] - Danio rerio [Complex:R-GGA-2317310] p-S-AKT:PIP3 [plasma membrane] - Gallus gallus [Complex:R-DME-2317310] p-S-AKT:PIP3 [plasma membrane] - Drosophila melanogaster [Complex:R-CEL-2317310] p-S-AKT:PIP3 [plasma membrane] - Caenorhabditis elegans [Complex:R-DDI-2317310] p-S-AKT:PIP3 [plasma membrane] - Dictyostelium discoideum [Complex:R-SPO-2317310] p-S-AKT:PIP3 [plasma membrane] - Schizosaccharomyces pombe [Complex:R-SCE-2317310] p-S-AKT:PIP3 [plasma membrane] - Saccharomyces cerevisiae
isChimeric	false
maxDepth	3
name	p-S-AKT:PIP3
producedByEvent	[Reaction:R-HSA-198640] mTORC2 phosphorylates AKT at S473 - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-2317310
updateTrackers	[UpdateTracker:9878768] Update Tracker - [Complex:2317310] p-S-AKT:PIP3 [plasma membrane] - v44:[updateContainedComponent]

(updatedInstance)	[UpdateTracker:9878768] Update Tracker - [Complex:2317310] p-S-AKT:PIP3 [plasma membrane] - v44:[updateContainedComponent]
(output)	[Reaction:R-HSA-198640] mTORC2 phosphorylates AKT at S473
(input)	[Reaction:R-HSA-2317314] AKT binds PDPK1
(hasComponent)	[Complex:R-HSA-2317313] p-S-AKT:PDPK1:PIP3 [plasma membrane]