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Pathway
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Entries
Visual phototransduction
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authored
[InstanceEdit:2187337] Jassal, B, 2012-04-09
created
[InstanceEdit:2187337] Jassal, B, 2012-04-09
dbId
2187338
diseasePathways
[Pathway:R-HSA-9918454] Defective visual phototransduction due to ABCA4 loss of function - Homo sapiens
[Pathway:R-HSA-9918438] Defective visual phototransduction due to RDH5 loss of function - Homo sapiens
[Pathway:R-HSA-9918436] Defective visual phototransduction due to OPN1MW loss of function - Homo sapiens
[Pathway:R-HSA-9918450] Defective visual phototransduction due to OPN1LW loss of function - Homo sapiens
[Pathway:R-HSA-9918449] Defective visual phototransduction due to STRA6 loss of function - Homo sapiens
[Pathway:R-HSA-9918443] Defective visual phototransduction due to OPN1SW loss of function - Homo sapiens
[Pathway:R-HSA-9918442] Defective visual phototransduction due to LRAT loss of function - Homo sapiens
[Pathway:R-HSA-2466712] Biosynthesis of A2E, implicated in retinal degradation - Homo sapiens
[Pathway:R-HSA-9918440] Defective visual phototransduction due to RDH12 loss of function - Homo sapiens
[Pathway:R-HSA-5619077] Defective SLC24A1 causes congenital stationary night blindness 1D (CSNB1D) - Homo sapiens
displayName
Visual phototransduction
doi
10.3180/REACT_160125.1
edited
[InstanceEdit:2187337] Jassal, B, 2012-04-09
eventOf
[TopLevelPathway:R-HSA-9709957] Sensory Perception - Homo sapiens
figure
[Figure:5659720] /figures/Pathway_Illustrations/illustration_phototransduction_72.png
goBiologicalProcess
[GO_BiologicalProcess:23641] phototransduction, visible light
hasDiagram
true
hasEHLD
false
hasEvent
[Pathway:R-HSA-975634] Retinoid metabolism and transport - Homo sapiens
[Pathway:R-HSA-2453902] The canonical retinoid cycle in rods (twilight vision) - Homo sapiens
[Pathway:R-HSA-2187335] The retinoid cycle in cones (daylight vision) - Homo sapiens
[Pathway:R-HSA-2514856] The phototransduction cascade - Homo sapiens
isInDisease
false
isInferred
false
lastUpdatedDate
2022-04-07
literatureReference
[LiteratureReference:975609] Mechanisms involved in the intestinal digestion and absorption of dietary vitamin A
[LiteratureReference:975630] Mechanisms of digestion and absorption of dietary vitamin A
[LiteratureReference:2464789] Metabolism of carotenoids and retinoids related to vision
[LiteratureReference:2464788] Overview of retinoid metabolism and function
[LiteratureReference:2464772] The biochemical and structural basis for trans-to-cis isomerization of retinoids in the chemistry of vision
[LiteratureReference:2425425] Vitamin A metabolism: an update
[LiteratureReference:2465918] Rod and cone visual pigments and phototransduction through pharmacological, genetic, and physiological approaches
[LiteratureReference:2465935] The cone-specific visual cycle
[LiteratureReference:2465923] The visual cycle of the cone photoreceptors of the retina
[LiteratureReference:3222200] Lessons from photoreceptors: turning off G-protein signaling in living cells
[LiteratureReference:3222188] Amplification and kinetics of the activation steps in phototransduction
[LiteratureReference:3222186] Speed, sensitivity, and stability of the light response in rod and cone photoreceptors: facts and models
maxDepth
4
modified
[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
name
Visual phototransduction
orthologousEvent
[Pathway:R-MMU-2187338] Visual phototransduction - Mus musculus
[Pathway:R-RNO-2187338] Visual phototransduction - Rattus norvegicus
[Pathway:R-CFA-2187338] Visual phototransduction - Canis familiaris
[Pathway:R-BTA-2187338] Visual phototransduction - Bos taurus
[Pathway:R-SSC-2187338] Visual phototransduction - Sus scrofa
[Pathway:R-DRE-2187338] Visual phototransduction - Danio rerio
[Pathway:R-XTR-2187338] Visual phototransduction - Xenopus tropicalis
[Pathway:R-GGA-2187338] Visual phototransduction - Gallus gallus
[Pathway:R-DME-2187338] Visual phototransduction - Drosophila melanogaster
[Pathway:R-CEL-2187338] Visual phototransduction - Caenorhabditis elegans
[Pathway:R-DDI-2187338] Visual phototransduction - Dictyostelium discoideum
[Pathway:R-SPO-2187338] Visual phototransduction - Schizosaccharomyces pombe
[Pathway:R-SCE-2187338] Visual phototransduction - Saccharomyces cerevisiae
[Pathway:R-PFA-2187338] Visual phototransduction - Plasmodium falciparum
releaseDate
2013-03-12
releaseStatus
UPDATED
reviewStatus
[ReviewStatus:9821382] five stars
schemaClass
Pathway
species
[Species:48887] Homo sapiens
stId
R-HSA-2187338
summation
[Summation:2395783] Visual phototransduction is the process by which photon abso...
updateTrackers
[UpdateTracker:9781356] Update Tracker - [Pathway:2187338] Visual phototransduction - v61:[updateIndirectRLE]
[UpdateTracker:9774912] Update Tracker - [Pathway:2187338] Visual phototransduction - v80:[updateIndirectRLE]
[UpdateTracker:9787494] Update Tracker - [Pathway:2187338] Visual phototransduction - v45:[addHasEvent, add_removeLiteratureReference, modifyText, updateIndirectRLE]
[UpdateTracker:9777534] Update Tracker - [Pathway:2187338] Visual phototransduction - v70:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9785414] Update Tracker - [Pathway:2187338] Visual phototransduction - v52:[updateContainedPathway]
[UpdateTracker:9781658] Update Tracker - [Pathway:2187338] Visual phototransduction - v60:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9783989] Update Tracker - [Pathway:2187338] Visual phototransduction - v55:[updateContainedPathway]
[UpdateTracker:9780246] Update Tracker - [Pathway:2187338] Visual phototransduction - v63:[updateIndirectRLE]
[UpdateTracker:9779986] Update Tracker - [Pathway:2187338] Visual phototransduction - v64:[updateIndirectRLE]
[UpdateTracker:9783090] Update Tracker - [Pathway:2187338] Visual phototransduction - v57:[updateIndirectRLE]
[UpdateTracker:9782316] Update Tracker - [Pathway:2187338] Visual phototransduction - v59:[updateIndirectRLE]
[UpdateTracker:9776942] Update Tracker - [Pathway:2187338] Visual phototransduction - v73:[updateIndirectRLE]
[UpdateTracker:9780788] Update Tracker - [Pathway:2187338] Visual phototransduction - v62:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9786744] Update Tracker - [Pathway:2187338] Visual phototransduction - v48:[updateContainedPathway, updateIndirectRLE]
Referrals
(hasEvent)
[TopLevelPathway:R-HSA-9709957] Sensory Perception
(hasEncapsulatedEvent)
[Pathway:R-HSA-975634] Retinoid metabolism and transport
(normalPathway)
[Pathway:R-HSA-9918454] Defective visual phototransduction due to ABCA4 loss of function
[Pathway:R-HSA-9918438] Defective visual phototransduction due to RDH5 loss of function
[Pathway:R-HSA-9918436] Defective visual phototransduction due to OPN1MW loss of function
[Pathway:R-HSA-9918450] Defective visual phototransduction due to OPN1LW loss of function
[Pathway:R-HSA-9918449] Defective visual phototransduction due to STRA6 loss of function
[Pathway:R-HSA-9918443] Defective visual phototransduction due to OPN1SW loss of function
[Pathway:R-HSA-9918442] Defective visual phototransduction due to LRAT loss of function
[Pathway:R-HSA-2466712] Biosynthesis of A2E, implicated in retinal degradation
[Pathway:R-HSA-9918440] Defective visual phototransduction due to RDH12 loss of function
[Pathway:R-HSA-5619077] Defective SLC24A1 causes congenital stationary night blindness 1D (CSNB1D)
(updatedInstance)
[UpdateTracker:9781356] Update Tracker - [Pathway:2187338] Visual phototransduction - v61:[updateIndirectRLE]
[UpdateTracker:9774912] Update Tracker - [Pathway:2187338] Visual phototransduction - v80:[updateIndirectRLE]
[UpdateTracker:9787494] Update Tracker - [Pathway:2187338] Visual phototransduction - v45:[addHasEvent, add_removeLiteratureReference, modifyText, updateIndirectRLE]
[UpdateTracker:9777534] Update Tracker - [Pathway:2187338] Visual phototransduction - v70:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9785414] Update Tracker - [Pathway:2187338] Visual phototransduction - v52:[updateContainedPathway]
[UpdateTracker:9781658] Update Tracker - [Pathway:2187338] Visual phototransduction - v60:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9783989] Update Tracker - [Pathway:2187338] Visual phototransduction - v55:[updateContainedPathway]
[UpdateTracker:9780246] Update Tracker - [Pathway:2187338] Visual phototransduction - v63:[updateIndirectRLE]
[UpdateTracker:9779986] Update Tracker - [Pathway:2187338] Visual phototransduction - v64:[updateIndirectRLE]
[UpdateTracker:9783090] Update Tracker - [Pathway:2187338] Visual phototransduction - v57:[updateIndirectRLE]
[UpdateTracker:9782316] Update Tracker - [Pathway:2187338] Visual phototransduction - v59:[updateIndirectRLE]
[UpdateTracker:9776942] Update Tracker - [Pathway:2187338] Visual phototransduction - v73:[updateIndirectRLE]
[UpdateTracker:9780788] Update Tracker - [Pathway:2187338] Visual phototransduction - v62:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9786744] Update Tracker - [Pathway:2187338] Visual phototransduction - v48:[updateContainedPathway, updateIndirectRLE]
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