Reactome | AGO2 [cytosol]

Schema > EntityWithAccessionedSequence > Entries

AGO2 [cytosol] Show undefined attributes

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-HSA-9657778] miR-144:AGO2 [cytosol] - Homo sapiens [Complex:R-HSA-4518566] miR92b endonucleolytic minimal RISC [cytosol] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-9820853] AGO2 binds maternal endosiRNA - Homo sapiens
created	[InstanceEdit:209722] May, B, 2008-01-06 21:41:43
dbId	209723
displayName	AGO2 [cytosol]
endCoordinate	859
inDisease	false
inferredTo	[EntityWithAccessionedSequence:R-MMU-209723] AGO2 [cytosol] - Mus musculus [EntityWithAccessionedSequence:R-RNO-209723] AGO2 [cytosol] - Rattus norvegicus [EntityWithAccessionedSequence:R-CFA-209723] AGO2 [cytosol] - Canis familiaris [EntityWithAccessionedSequence:R-BTA-209723] AGO2 [cytosol] - Bos taurus [EntityWithAccessionedSequence:R-SSC-209723] AGO2 [cytosol] - Sus scrofa [EntityWithAccessionedSequence:R-XTR-209723] AGO2 [cytosol] - Xenopus tropicalis [EntityWithAccessionedSequence:R-GGA-209723] AGO2 [cytosol] - Gallus gallus [EntityWithAccessionedSequence:R-DME-209723] AGO1 [cytosol] - Drosophila melanogaster [EntityWithAccessionedSequence:R-CEL-209723] alg-1 [cytosol] - Caenorhabditis elegans [EntityWithAccessionedSequence:R-SPO-209723] ago1 [cytosol] - Schizosaccharomyces pombe
maxDepth	1
memberOf	[CandidateSet:R-HSA-629636] AGO1,2,3,4 [cytosol] - Homo sapiens
modified	[InstanceEdit:9615777] Orlic-Milacic, Marija, 2018-08-08
name	AGO2 EIF2C2 Argonaute-2
referenceEntity	[ReferenceGeneProduct:uniprot:Q9UKV8] UniProt:Q9UKV8 AGO2
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-209723
startCoordinate	1
updateTrackers	[UpdateTracker:9887719] Update Tracker - [EntityWithAccessionedSequence:209723] AGO2 [cytosol] - v46:[addName] [UpdateTracker:9885843] Update Tracker - [EntityWithAccessionedSequence:209723] AGO2 [cytosol] - v45:[addName] [UpdateTracker:9877024] Update Tracker - [EntityWithAccessionedSequence:209723] AGO2 [cytosol] - v44:[modifyEndCoordinate]

Referrals

(hasComponent)	[Complex:R-HSA-9657778] miR-144:AGO2 [cytosol] [Complex:R-HSA-9038549] miR-613:AGO2 [cytosol] [Complex:R-HSA-9624932] miR-33A:AGO2 [cytosol] [Complex:R-HSA-9624930] miR-33B:AGO2 [cytosol] [Complex:R-HSA-9011857] miR-26B Endonucleolytic Minimal RISC [cytosol] [Complex:R-HSA-9860152] miR-27b Endonucleolytic Minimal RISC [cytosol] [Complex:R-HSA-9614881] miR-23b Endonucleolytic Minimal RISC [cytosol] [Complex:R-HSA-9850910] miR-21 Endonucleolytic minimal RISC [cytosol] [Complex:R-HSA-9858263] mir-211 Endonucleolytic Minimal RISC [cytosol] [Complex:R-HSA-9820885] AGO2:maternal endosiRNA [cytosol] [Complex:R-HSA-9769451] miR-224-5p Endonucleolytic Minimal RISC [cytosol] [Complex:R-HSA-9021195] miR-132 Endonucleolytic Minimal RISC [cytosol] [Complex:R-HSA-9615667] miR-137 Endonucleolytic Minimal RISC [cytosol] [Complex:R-HSA-9925340] miR-138-5p Endonucleolytic Minimal RISC [cytosol] [Complex:R-HSA-9924993] miR-429 Endonucleolytic Minimal RISC [cytosol] [Complex:R-HSA-9925189] miR-152 Endonucleolytic Minimal RISC [cytosol] [Complex:R-HSA-9860105] miR-Let7-a1 Endonucleolytic Minimal RISC [cytosol] [Complex:R-HSA-9925202] miR-340 Endonucleolytic Minimal RISC [cytosol] [Complex:R-HSA-9925235] miR-148a-3p Endonucleolytic Minimal RISC [cytosol] [Complex:R-HSA-9925219] miR-142-5p Endonucleolytic Minimal RISC [cytosol] [Complex:R-HSA-9925048] miR-424 Endonucleolytic Minimal RISC [cytosol] [Complex:R-HSA-9924946] miR-140 Endonucleolytic Minimal RISC [cytosol] [Complex:R-HSA-2318741] miR-26A Endonucleolytic Minimal RISC [cytosol] [Complex:R-HSA-8948551] miR-19a Endonucleolytic Minimal RISC [cytosol] [Complex:R-HSA-8944536] miR-22 Endonucleolytic Minimal RISC [cytosol] [Complex:R-HSA-8945710] miR-20 Endonucleolytic Minimal RISC [cytosol] [Complex:R-HSA-8944482] miR-17 Endonucleolytic Minimal RISC [cytosol] [Complex:R-HSA-8944591] miR-93 Endonucleolytic Minimal RISC [cytosol] [Complex:R-HSA-8944668] miR-205 Endonucleolytic Minimal RISC [cytosol] [Complex:R-HSA-8944621] miR-106 Endonucleolytic Minimal RISC [cytosol] [Complex:R-HSA-8944514] miR-19b Endonucleolytic Minimal RISC [cytosol] [Complex:R-HSA-8944567] miR-25 Endonucleolytic Minimal RISC [cytosol] [Complex:R-HSA-1606688] miR-34 Endonucleolytic Minimal RISC [cytosol] [Complex:R-HSA-1606549] miR-449 Endonucleolytic Minimal RISC [cytosol] [Complex:R-HSA-1614235] miR-200B/C Endonucleolytic Minimal RISC [cytosol] [Complex:R-HSA-1852610] miR-150 Endonucleolytic Minimal RISC [cytosol] [Complex:R-HSA-1614233] miR-206 Endonucleolytic Minimal RISC [cytosol] [Complex:R-HSA-1852595] miR-302A Endonucleolytic Minimal RISC [cytosol] [Complex:R-HSA-1852601] miR-181C Endonucleolytic Minimal RISC [cytosol] [Complex:R-HSA-8936043] miR-675 Endonucleolytic Minimal RISC [cytosol] [Complex:R-HSA-8935860] miR-302b Endonucleolytic Minimal RISC [cytosol] [Complex:R-HSA-8935929] miR-18a Endonucleolytic Minimal RISC [cytosol] [Complex:R-HSA-8939108] miR-215 Endonucleolytic Minimal RISC [cytosol] [Complex:R-HSA-4518566] miR92b endonucleolytic minimal RISC [cytosol] [Complex:R-HSA-9759792] miR-451a Endonucleolytic Minimal RISC [cytosol] [Complex:R-HSA-9759978] miR-200c-3p Endonucleolytic Minimal RISC [cytosol] [Complex:R-HSA-9621493] miR-9-5p Endonucleolytic Minimal RISC [cytosol] [Complex:R-HSA-9816177] miR-10b-5p Endonucleolytic Minimal RISC [cytosol] [Complex:R-HSA-2106605] AGO2:duplex siRNA [cytosol] [Complex:R-HSA-9023915] AGO2:cleaved duplex siRNA [cytosol] [Complex:R-HSA-2106601] AGO2:siRNA [cytosol] [Complex:R-HSA-2106621] AGO2:miRNA [cytosol] [Complex:R-HSA-2106619] AGO2:duplex miRNA [cytosol] [Complex:R-HSA-9982552] miR-142-3p Endonucleolytic Minimal RISC [cytosol] [Complex:R-HSA-5687046] miR-34B,C Endonucleolytic Minimal RISC [cytosol]
(input)	[Reaction:R-HSA-9820853] AGO2 binds maternal endosiRNA
(hasMember)	[CandidateSet:R-HSA-629636] AGO1,2,3,4 [cytosol]
(activeUnit)	[CatalystActivity:9820851] endoribonuclease activity, cleaving siRNA-paired mRNA of AGO2:maternal endosiRNA [cytosol] [CatalystActivity:426499] RNA endonuclease activity of Endonucleolytic RISC [cytosol]
(updatedInstance)	[UpdateTracker:9887719] Update Tracker - [EntityWithAccessionedSequence:209723] AGO2 [cytosol] - v46:[addName] [UpdateTracker:9885843] Update Tracker - [EntityWithAccessionedSequence:209723] AGO2 [cytosol] - v45:[addName] [UpdateTracker:9877024] Update Tracker - [EntityWithAccessionedSequence:209723] AGO2 [cytosol] - v44:[modifyEndCoordinate]

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