Reactome | FCGR activation

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FCGR activation Show undefined attributes

authored	[InstanceEdit:2029483] Garapati, P V, 2012-01-04
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol
created	[InstanceEdit:2029483] Garapati, P V, 2012-01-04
dbId	2029481
displayName	FCGR activation
edited	[InstanceEdit:2029483] Garapati, P V, 2012-01-04
eventOf	[Pathway:R-HSA-2029480] Fcgamma receptor (FCGR) dependent phagocytosis - Homo sapiens
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-HSA-2029455] Cross-linking of FCGRIA with IgG-coated Ag - Homo sapiens [Reaction:R-HSA-1861621] Cross-linking of FCGRIIA with IgG-coated Ag - Homo sapiens [Reaction:R-HSA-2029457] Cross-linking of FCGRIIIA with IgG-coated Ag - Homo sapiens [BlackBoxEvent:R-HSA-2029459] Sequestering and phosphorylation Fc gamma receptors in the lipid rafts - Homo sapiens [Reaction:R-HSA-2029452] Recruitment of SYK to phosphorylated ITAMs - Homo sapiens [Reaction:R-HSA-2029449] Phosphorylation of SYK by Src kinases - Homo sapiens
isInDisease	false
isInferred	false
lastUpdatedDate	2020-03-16
literatureReference	[LiteratureReference:2028811] Fcgamma receptor signaling in phagocytes [LiteratureReference:2028829] Molecular mechanisms of phagocytic uptake in mammalian cells [LiteratureReference:1861545] Signal transduction during Fc receptor-mediated phagocytosis
maxDepth	2
modified	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
name	FCGR activation
orthologousEvent	[Pathway:R-MMU-2029481] FCGR activation - Mus musculus [Pathway:R-GGA-2029481] FCGR activation - Gallus gallus [Pathway:R-SSC-2029481] FCGR activation - Sus scrofa [Pathway:R-BTA-2029481] FCGR activation - Bos taurus [Pathway:R-CFA-2029481] FCGR activation - Canis familiaris [Pathway:R-RNO-2029481] FCGR activation - Rattus norvegicus
releaseDate	2013-03-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:2248842] Rosales, C, 2012-05-14
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-2029481
summation	[Summation:2028807] Cross-linking of FCGRs with IgG coated immune complexes resu...
updateTrackers	[UpdateTracker:9777321] Update Tracker - [Pathway:2029481] FCGR activation - v72:[updateContainedRLE]

Referrals

(updatedInstance)	[UpdateTracker:9777321] Update Tracker - [Pathway:2029481] FCGR activation - v72:[updateContainedRLE]
(hasEvent)	[Pathway:R-HSA-2029480] Fcgamma receptor (FCGR) dependent phagocytosis