Reactome | Cross-linking of FCGRIIA with IgG-coated Ag

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Cross-linking of FCGRIIA with IgG-coated Ag Show undefined attributes

authored	[InstanceEdit:2029483] Garapati, P V, 2012-01-04
category	binding
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:1861649] Garapati, P V, 2011-10-31
dbId	1861621
displayName	Cross-linking of FCGRIIA with IgG-coated Ag
edited	[InstanceEdit:2029483] Garapati, P V, 2012-01-04
eventOf	[Pathway:R-HSA-2029481] FCGR activation - Homo sapiens
followingEvent	[BlackBoxEvent:R-HSA-2029459] Sequestering and phosphorylation Fc gamma receptors in the lipid rafts - Homo sapiens
input	[Complex:R-HSA-173552] Antigen:IgG [plasma membrane] [EntityWithAccessionedSequence:R-HSA-197838] FCGR2A [plasma membrane]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:1861708] Structure and expression of human IgG FcRII(CD32). Functional heterogeneity is encoded by the alternatively spliced products of multiple genes [LiteratureReference:1861716] Substitutions and deletions in the cytoplasmic domain of the phagocytic receptor Fc gamma RIIA: effect on receptor tyrosine phosphorylation and phagocytosis [LiteratureReference:1861628] Identification of signaling motifs within human Fc gamma RIIa and Fc gamma RIIb isoforms
maxDepth	1
modified	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
name	Cross-linking of FCGRIIA with IgG-coated Ag
orthologousEvent	[Reaction:R-MMU-1861621] Cross-linking of FCGRIIA with IgG-coated Ag - Mus musculus [Reaction:R-GGA-1861621] Cross-linking of FCGRIIA with IgG-coated Ag - Gallus gallus [Reaction:R-SSC-1861621] Cross-linking of FCGRIIA with IgG-coated Ag - Sus scrofa [Reaction:R-BTA-1861621] Cross-linking of FCGRIIA with IgG-coated Ag - Bos taurus [Reaction:R-CFA-1861621] Cross-linking of FCGRIIA with IgG-coated Ag - Canis familiaris [Reaction:R-RNO-1861621] Cross-linking of FCGRIIA with IgG-coated Ag - Rattus norvegicus
output	[Complex:R-HSA-1861689] IgG-Ag:FCGRIIA [plasma membrane]
releaseDate	2013-03-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:2248842] Rosales, C, 2012-05-14
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-1861621
summation	[Summation:1861599] FCGRII (CD32) is a low-affinity receptor encoded by three di...

Referrals

(hasEvent)	[Pathway:R-HSA-2029481] FCGR activation
(precedingEvent)	[BlackBoxEvent:R-HSA-2029459] Sequestering and phosphorylation Fc gamma receptors in the lipid rafts