Reactome | Phosphorylation of VAV

Schema > Reaction > Entries

Phosphorylation of VAV Show undefined attributes

authored	[InstanceEdit:2029483] Garapati, P V, 2012-01-04
catalystActivity	[CatalystActivity:2029260] protein tyrosine kinase activity of clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane]
category	transition
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol [Compartment:984] extracellular region
created	[InstanceEdit:2029450] Garapati, P V, 2012-01-04
dbId	2029453
displayName	Phosphorylation of VAV
edited	[InstanceEdit:2029483] Garapati, P V, 2012-01-04
eventOf	[Pathway:R-HSA-2029482] Regulation of actin dynamics for phagocytic cup formation - Homo sapiens
followingEvent	[Reaction:R-HSA-2029451] Activation of RAC1 by VAV - Homo sapiens
input	[SimpleEntity:R-ALL-113592] ATP [cytosol] [Complex:R-HSA-2029133] clustered IgG-Ag:p-FCGRs:p-6Y-SYK:VAV [plasma membrane]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:2028947] Vav in natural killer cells is tyrosine phosphorylated upon cross-linking of Fc gamma RIIIA and is constitutively associated with a serine/threonine kinase
maxDepth	1
modified	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
name	Phosphorylation of VAV
orthologousEvent	[Reaction:R-MMU-2029453] Phosphorylation of VAV - Mus musculus [Reaction:R-GGA-2029453] Phosphorylation of VAV - Gallus gallus [Reaction:R-SSC-2029453] Phosphorylation of VAV - Sus scrofa [Reaction:R-BTA-2029453] Phosphorylation of VAV - Bos taurus [Reaction:R-CFA-2029453] Phosphorylation of VAV - Canis familiaris [Reaction:R-RNO-2029453] Phosphorylation of VAV - Rattus norvegicus
output	[SimpleEntity:R-ALL-29370] ADP [cytosol] [Complex:R-HSA-2029131] clustered IgG-Ag:p-FCGRs:p-6Y-SYK:p-VAV [plasma membrane]
releaseDate	2013-03-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:2248842] Rosales, C, 2012-05-14
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-2029453
summation	[Summation:2028828] VAV proteins exist in an auto-inhibitory state folded in suc...

Referrals

(hasEvent)	[Pathway:R-HSA-2029482] Regulation of actin dynamics for phagocytic cup formation
(precedingEvent)	[Reaction:R-HSA-2029451] Activation of RAC1 by VAV