Reactome | FKBP1A:tacrolimus [cytosol]

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FKBP1A:tacrolimus [cytosol] Show undefined attributes

compartment	[Compartment:70101] cytosol
created	[InstanceEdit:2026006] May, B, 2011-12-20
dbId	2026019
deleted	[Deleted:9690503] Deletion of instance: 9690458
displayName	FKBP1A:tacrolimus [cytosol]
hasComponent	[EntityWithAccessionedSequence:R-HSA-2026007] FKBP1A [cytosol] [ChemicalDrug:R-ALL-9678991] tacrolimus [cytosol]
inDisease	false
inferredTo	[Complex:R-MMU-2026019] FKBP1A:tacrolimus [cytosol] - Mus musculus [Complex:R-RNO-2026019] FKBP1A:tacrolimus [cytosol] - Rattus norvegicus [Complex:R-CFA-2026019] FKBP1A:tacrolimus [cytosol] - Canis familiaris [Complex:R-BTA-2026019] FKBP1A:tacrolimus [cytosol] - Bos taurus [Complex:R-SSC-2026019] FKBP1A:tacrolimus [cytosol] - Sus scrofa [Complex:R-DRE-2026019] FKBP1A:tacrolimus [cytosol] - Danio rerio [Complex:R-GGA-2026019] FKBP1A:tacrolimus [cytosol] - Gallus gallus [Complex:R-DME-2026019] FKBP1A:tacrolimus [cytosol] - Drosophila melanogaster [Complex:R-CEL-2026019] FKBP1A:tacrolimus [cytosol] - Caenorhabditis elegans [Complex:R-DDI-2026019] FKBP1A:tacrolimus [cytosol] - Dictyostelium discoideum [Complex:R-SPO-2026019] FKBP1A:tacrolimus [cytosol] - Schizosaccharomyces pombe [Complex:R-SCE-2026019] FKBP1A:tacrolimus [cytosol] - Saccharomyces cerevisiae
isChimeric	false
literatureReference	[LiteratureReference:2026028] Crystal structures of human calcineurin and the human FKBP12-FK506-calcineurin complex
maxDepth	2
modified	[InstanceEdit:9690601] Jassal, Bijay, 2020-06-03
name	FKBP1A:tacrolimus
negativelyRegulates	[NegativeRegulation:R-HSA-2026021] Negative regulation by 'FKBP1A:tacrolimus [cytosol]'
producedByEvent	[Reaction:R-HSA-9690461] FKBP1A binds tacrolimus - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-2026019
updateTrackers	[UpdateTracker:9901574] Update Tracker - [Complex:2026019] FKBP1A:tacrolimus [cytosol] - v74:[add_removeHasComponent, modifyName]

Referrals

(updatedInstance)	[UpdateTracker:9901574] Update Tracker - [Complex:2026019] FKBP1A:tacrolimus [cytosol] - v74:[add_removeHasComponent, modifyName]
(replacementInstances)	[Deleted:9690503] Deletion of instance: 9690458
(regulator)	[NegativeRegulation:R-HSA-2026021] Negative regulation by 'FKBP1A:tacrolimus [cytosol]'
(output)	[Reaction:R-HSA-9690461] FKBP1A binds tacrolimus

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