Reactome | p-8Y- FGFR1 R576W [plasma membrane]

Schema > EntityWithAccessionedSequence > Entries

p-8Y- FGFR1 R576W [plasma membrane] Show undefined attributes

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-HSA-2023430] p-8Y-FGFR1 R576W dimer [plasma membrane] - Homo sapiens [Complex:R-HSA-2023430] p-8Y-FGFR1 R576W dimer [plasma membrane] - Homo sapiens
created	[InstanceEdit:2023360] Rothfels, K, 2011-12-07
crossReference	[DatabaseIdentifier:12020790] Mondo:0018177
dbId	2023361
disease	[Disease:1500689] cancer [Disease:1247632] glioblastoma
displayName	p-8Y- FGFR1 R576W [plasma membrane]
endCoordinate	822
hasModifiedResidue	[ModifiedResidue:1838976] O4'-phospho-L-tyrosine at 766 [ModifiedResidue:2011867] O4'-phospho-L-tyrosine at 463 [ModifiedResidue:2011863] O4'-phospho-L-tyrosine at 583 [ModifiedResidue:2011864] O4'-phospho-L-tyrosine at 585 [ModifiedResidue:2011862] O4'-phospho-L-tyrosine at 653 [ModifiedResidue:2011865] O4'-phospho-L-tyrosine at 654 [ModifiedResidue:2011860] O4'-phospho-L-tyrosine at 730 [ModifiedResidue:2011859] O4'-phospho-L-tyrosine at 776 [ReplacedResidue:2011842] L-arginine 576 replaced with L-tryptophan
inDisease	true
maxDepth	1
modified	[InstanceEdit:9962055] Matthews, Lisa, 2025-07-30
name	p-8Y- FGFR1 R576W
referenceEntity	[ReferenceGeneProduct:uniprot:P11362] UniProt:P11362 FGFR1
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-2023361
startCoordinate	22
updateTrackers	[UpdateTracker:9964824] Update Tracker - [EntityWithAccessionedSequence:2023361] p-8Y- FGFR1 R576W [plasma membrane] - v94:[add_removeDisease] [UpdateTracker:9889957] Update Tracker - [EntityWithAccessionedSequence:2023361] p-8Y- FGFR1 R576W [plasma membrane] - v52:[modifyName, removeHasModifiedResidue]

Referrals

(updatedInstance)	[UpdateTracker:9964824] Update Tracker - [EntityWithAccessionedSequence:2023361] p-8Y- FGFR1 R576W [plasma membrane] - v94:[add_removeDisease] [UpdateTracker:9889957] Update Tracker - [EntityWithAccessionedSequence:2023361] p-8Y- FGFR1 R576W [plasma membrane] - v52:[modifyName, removeHasModifiedResidue]
(hasComponent)	[Complex:R-HSA-2023430] p-8Y-FGFR1 R576W dimer [plasma membrane]