Reactome | GSK3B [nucleoplasm]

Schema > EntityWithAccessionedSequence > Entries

GSK3B [nucleoplasm] Show undefined attributes

catalystActivities	[CatalystActivity:2022841] protein serine/threonine kinase activity of GSK3B [nucleoplasm]
compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-NUL-9008638] p-S369,S373,S377-Runx2:GSK3B [nucleoplasm] - Homo sapiens
consumedByEvent	[Reaction:R-NUL-9008555] Runx2 binds GSK3B - Mus musculus [Reaction:R-HSA-9008476] RUNX2 binds GSK3B - Homo sapiens
created	[InstanceEdit:2022824] May, B, 2011-12-01
dbId	2022823
displayName	GSK3B [nucleoplasm]
endCoordinate	420
inDisease	false
inferredTo	[EntityWithAccessionedSequence:R-MMU-182565] Gsk3b [nucleoplasm] - Mus musculus [EntityWithAccessionedSequence:R-RNO-2022823] GSK3B [nucleoplasm] - Rattus norvegicus [EntityWithAccessionedSequence:R-CFA-2022823] GSK3B [nucleoplasm] - Canis familiaris [EntityWithAccessionedSequence:R-BTA-2022823] GSK3B [nucleoplasm] - Bos taurus [EntityWithAccessionedSequence:R-SSC-2022823] GSK3B [nucleoplasm] - Sus scrofa [EntityWithAccessionedSequence:R-DRE-2022823] GSK3B [nucleoplasm] - Danio rerio [EntityWithAccessionedSequence:R-XTR-2022823] GSK3B [nucleoplasm] - Xenopus tropicalis [EntityWithAccessionedSequence:R-GGA-2022823] GSK3B [nucleoplasm] - Gallus gallus [EntityWithAccessionedSequence:R-DME-2022823] GSK3B [nucleoplasm] - Drosophila melanogaster [EntityWithAccessionedSequence:R-DME-2022823-2] GSK3B [nucleoplasm] - Drosophila melanogaster [DefinedSet:R-DME-2022823-3] Homologues of GSK3B [nucleoplasm] - Drosophila melanogaster [EntityWithAccessionedSequence:R-CEL-2022823] GSK3B [nucleoplasm] - Caenorhabditis elegans [EntityWithAccessionedSequence:R-CEL-2022823-2] GSK3B [nucleoplasm] - Caenorhabditis elegans [EntityWithAccessionedSequence:R-CEL-2022823-3] GSK3B [nucleoplasm] - Caenorhabditis elegans [DefinedSet:R-CEL-2022823-4] Homologues of GSK3B [nucleoplasm] - Caenorhabditis elegans [EntityWithAccessionedSequence:R-DDI-2022823] GSK3B [nucleoplasm] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-SPO-2022823] GSK3B [nucleoplasm] - Schizosaccharomyces pombe [EntityWithAccessionedSequence:R-SPO-2022823-2] GSK3B [nucleoplasm] - Schizosaccharomyces pombe [DefinedSet:R-SPO-2022823-3] Homologues of GSK3B [nucleoplasm] - Schizosaccharomyces pombe [EntityWithAccessionedSequence:R-SCE-2022823] GSK3B [nucleoplasm] - Saccharomyces cerevisiae [EntityWithAccessionedSequence:R-SCE-2022823-2] GSK3B [nucleoplasm] - Saccharomyces cerevisiae [EntityWithAccessionedSequence:R-SCE-2022823-3] GSK3B [nucleoplasm] - Saccharomyces cerevisiae [DefinedSet:R-SCE-2022823-4] Homologues of GSK3B [nucleoplasm] - Saccharomyces cerevisiae
literatureReference	[LiteratureReference:6808625] Glycogen synthase kinase (GSK) 3? phosphorylates and protects nuclear myosin 1c from proteasome-mediated degradation to activate rDNA transcription in early G1 cells
maxDepth	1
modified	[InstanceEdit:6808628] May, Bruce, 2015-11-07
name	GSK3B Glycogen synthase kinase-3 beta GSK3B_HUMAN
positivelyRegulates	[PositiveRegulation:R-HSA-6808617] Positive regulation by 'GSK3B [nucleoplasm]'
referenceEntity	[ReferenceGeneProduct:uniprot:P49841] UniProt:P49841 GSK3B
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-2022823
startCoordinate	1

Referrals

(regulator)	[PositiveRegulation:R-HSA-6808617] Positive regulation by 'GSK3B [nucleoplasm]'
(hasComponent)	[Complex:R-NUL-9008638] p-S369,S373,S377-Runx2:GSK3B [nucleoplasm] [Complex:R-HSA-9008635] p-3S-RUNX2:GSK3B [nucleoplasm] [Complex:R-NUL-9008554] Runx2:GSK3B [nucleoplasm] [Complex:R-HSA-9008489] RUNX2:GSK3B [nucleoplasm]
(activeUnit)	[CatalystActivity:9008645] protein serine/threonine kinase activity of Runx2:GSK3B [nucleoplasm] [CatalystActivity:9008633] protein serine/threonine kinase activity of RUNX2:GSK3B [nucleoplasm]
(input)	[Reaction:R-NUL-9008555] Runx2 binds GSK3B [Reaction:R-HSA-9008476] RUNX2 binds GSK3B
(physicalEntity)	[CatalystActivity:2022841] protein serine/threonine kinase activity of GSK3B [nucleoplasm]

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