Reactome | p-T,p-S-AKT [nucleoplasm]

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p-T,p-S-AKT [nucleoplasm] Show undefined attributes

catalystActivities	[CatalystActivity:199274] protein serine/threonine kinase activity of p-T,p-S-AKT [nucleoplasm]
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:202071] Jassal, B, 2007-10-18 12:38:34
dbId	202072
displayName	p-T,p-S-AKT [nucleoplasm]
hasCandidate	[EntityWithAccessionedSequence:R-HSA-202087] p-T309,S474-AKT2 [nucleoplasm] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-3009365] p-T305,S472-AKT3 [nucleoplasm] - Homo sapiens
hasMember	[EntityWithAccessionedSequence:R-HSA-198357] p-T308,S473-AKT1 [nucleoplasm] - Homo sapiens
inDisease	false
inferredTo	[CandidateSet:R-MMU-202072] p-T,p-S-AKT [nucleoplasm] - Mus musculus [CandidateSet:R-RNO-202072] p-T,p-S-AKT [nucleoplasm] - Rattus norvegicus [CandidateSet:R-DRE-202072] p-T,p-S-AKT [nucleoplasm] - Danio rerio [EntityWithAccessionedSequence:R-GGA-198357] phospho-p-T308,S473-AKT1 [nucleoplasm] - Gallus gallus [CandidateSet:R-DME-202072] p-T,p-S-AKT [nucleoplasm] - Drosophila melanogaster [CandidateSet:R-CEL-202072] p-T,p-S-AKT [nucleoplasm] - Caenorhabditis elegans [CandidateSet:R-DDI-202072] p-T,p-S-AKT [nucleoplasm] - Dictyostelium discoideum [CandidateSet:R-SPO-202072] p-T,p-S-AKT [nucleoplasm] - Schizosaccharomyces pombe [CandidateSet:R-SCE-202072] p-T,p-S-AKT [nucleoplasm] - Saccharomyces cerevisiae
maxDepth	2
modified	[InstanceEdit:9622731] Orlic-Milacic, Marija, 2018-10-01
name	p-T,p-S-AKT Active AKT p-T308,S473-AKT1,(p-T309,S474-AKT2,p-T305,S472-AKT3)
negativelyRegulates	[NegativeRegulation:R-HSA-6805635] Negative regulation by 'p-T, p-S-AKT [nucleoplasm]'
producedByEvent	[Reaction:R-HSA-198298] AKT translocates to the nucleus - Homo sapiens
schemaClass	CandidateSet
species	[Species:48887] Homo sapiens
stId	R-HSA-202072
updateTrackers	[UpdateTracker:9876091] Update Tracker - [CandidateSet:202072] p-T,p-S-AKT [nucleoplasm] - v44:[add_removeHasCandidate] [UpdateTracker:9899290] Update Tracker - [CandidateSet:202072] p-T,p-S-AKT [nucleoplasm] - v65:[addName] [UpdateTracker:9899614] Update Tracker - [CandidateSet:202072] p-T,p-S-AKT [nucleoplasm] - v67:[modifyName] [UpdateTracker:9899559] Update Tracker - [CandidateSet:202072] p-T,p-S-AKT [nucleoplasm] - v66:[addName]

Referrals

(updatedInstance)	[UpdateTracker:9876091] Update Tracker - [CandidateSet:202072] p-T,p-S-AKT [nucleoplasm] - v44:[add_removeHasCandidate] [UpdateTracker:9899290] Update Tracker - [CandidateSet:202072] p-T,p-S-AKT [nucleoplasm] - v65:[addName] [UpdateTracker:9899614] Update Tracker - [CandidateSet:202072] p-T,p-S-AKT [nucleoplasm] - v67:[modifyName] [UpdateTracker:9899559] Update Tracker - [CandidateSet:202072] p-T,p-S-AKT [nucleoplasm] - v66:[addName]
(normalEntity)	[EntityFunctionalStatus:2400003] gain_of_function of p-T308,S473-AKT1 E17K [nucleoplasm]
(regulator)	[NegativeRegulation:R-HSA-6805635] Negative regulation by 'p-T, p-S-AKT [nucleoplasm]'
(output)	[Reaction:R-HSA-198298] AKT translocates to the nucleus
(physicalEntity)	[CatalystActivity:199274] protein serine/threonine kinase activity of p-T,p-S-AKT [nucleoplasm]

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