Reactome | p-6Y-FGFR3 Y373C [plasma membrane]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-HSA-2011986] Activated FGFR3 Y373C mutant dimer [plasma membrane] - Homo sapiens [Complex:R-HSA-2011986] Activated FGFR3 Y373C mutant dimer [plasma membrane] - Homo sapiens
created	[InstanceEdit:2011888] Rothfels, K, 2011-11-22
crossReference	[DatabaseIdentifier:12021294] Mondo:0017042
dbId	2011889
disease	[Disease:1493885] bladder carcinoma [Disease:1614388] multiple myeloma [Disease:1625209] thanatophoric dysplasia
displayName	p-6Y-FGFR3 Y373C [plasma membrane]
endCoordinate	806
hasModifiedResidue	[ReplacedResidue:1614423] L-tyrosine 373 replaced with L-cysteine [ModifiedResidue:1307975] O4'-phospho-L-tyrosine at 577 [ModifiedResidue:1307875] O4'-phospho-L-tyrosine at 647 [ModifiedResidue:1307866] O4'-phospho-L-tyrosine at 648 [ModifiedResidue:1307886] O4'-phospho-L-tyrosine at 724 [ModifiedResidue:1307891] O4'-phospho-L-tyrosine at 760 [ModifiedResidue:1307897] O4'-phospho-L-tyrosine at 770
inDisease	true
maxDepth	1
modified	[InstanceEdit:5649602] Rothfels, Karen, 2014-11-20
name	p-6Y-FGFR3 Y373C
referenceEntity	[ReferenceGeneProduct:uniprot:P22607] UniProt:P22607 FGFR3
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-2011889
startCoordinate	23
updateTrackers	[UpdateTracker:9891087] Update Tracker - [EntityWithAccessionedSequence:2011889] p-6Y-FGFR3 Y373C [plasma membrane] - v52:[modifyName]

(updatedInstance)	[UpdateTracker:9891087] Update Tracker - [EntityWithAccessionedSequence:2011889] p-6Y-FGFR3 Y373C [plasma membrane] - v52:[modifyName]
(hasComponent)	[Complex:R-HSA-2011986] Activated FGFR3 Y373C mutant dimer [plasma membrane]

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