Reactome | SLC25A32 transports THF from mitochondrial matrix to cytosol

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SLC25A32 transports THF from mitochondrial matrix to cytosol Show undefined attributes

catalystActivity	[CatalystActivity:200687] folic acid transmembrane transporter activity of SLC25A32 [mitochondrial inner membrane]
category	transition
compartment	[Compartment:70616] mitochondrial inner membrane
created	[InstanceEdit:200727] D'Eustachio, P, 2007-07-23 20:23:04
dbId	200720
displayName	SLC25A32 transports THF from mitochondrial matrix to cytosol
eventOf	[Pathway:R-HSA-196757] Metabolism of folate and pterines - Homo sapiens
input	[SimpleEntity:R-ALL-200671] THF [mitochondrial matrix]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:200723] Retrovirally mediated complementation of the glyB phenotype. Cloning of a human gene encoding the carrier for entry of folates into mitochondria. [LiteratureReference:200690] Purification and properties of human cytosolic folylpoly-gamma-glutamate synthetase and organization, localization, and differential splicing of its gene
maxDepth	1
modified	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
name	SLC25A32 transports THF from mitochondrial matrix to cytosol Mitochondrial tetrahydrofolate export across the inner mitochondrial membrane
orthologousEvent	[Reaction:R-PFA-200720] SLC25A32 transports THF from mitochondrial matrix to cytosol - Plasmodium falciparum [Reaction:R-SCE-200720] SLC25A32 transports THF from mitochondrial matrix to cytosol - Saccharomyces cerevisiae [Reaction:R-SPO-200720] SLC25A32 transports THF from mitochondrial matrix to cytosol - Schizosaccharomyces pombe [Reaction:R-DDI-200720] SLC25A32 transports THF from mitochondrial matrix to cytosol - Dictyostelium discoideum [Reaction:R-CEL-200720] SLC25A32 transports THF from mitochondrial matrix to cytosol - Caenorhabditis elegans [Reaction:R-DME-200720] SLC25A32 transports THF from mitochondrial matrix to cytosol - Drosophila melanogaster [Reaction:R-GGA-200720] SLC25A32 transports THF from mitochondrial matrix to cytosol - Gallus gallus [Reaction:R-XTR-200720] SLC25A32 transports THF from mitochondrial matrix to cytosol - Xenopus tropicalis [Reaction:R-DRE-200720] SLC25A32 transports THF from mitochondrial matrix to cytosol - Danio rerio [Reaction:R-SSC-200720] SLC25A32 transports THF from mitochondrial matrix to cytosol - Sus scrofa [Reaction:R-BTA-200720] SLC25A32 transports THF from mitochondrial matrix to cytosol - Bos taurus [Reaction:R-CFA-200720] SLC25A32 transports THF from mitochondrial matrix to cytosol - Canis familiaris [Reaction:R-RNO-200720] SLC25A32 transports THF from mitochondrial matrix to cytosol - Rattus norvegicus [Reaction:R-MMU-200720] SLC25A32 transports THF from mitochondrial matrix to cytosol - Mus musculus
output	[SimpleEntity:R-ALL-111355] THF [cytosol]
releaseDate	2007-08-21
reviewStatus	[ReviewStatus:9821382] five stars
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-200720
summation	[Summation:200728] SLC25A32 protein in the inner mitochondrial membrane mediate...

Referrals

(hasEvent)	[Pathway:R-HSA-196757] Metabolism of folate and pterines
(reverseReaction)	[Reaction:R-HSA-200680] SLC25A32 transports THF from cytosol to mitochondrial matrix