Reactome | Formation of allysine by LOX

Schema > Reaction > Entries

Formation of allysine by LOX Show undefined attributes

authored	[InstanceEdit:2214334] Jupe, S, 2012-04-30
catalystActivity	[CatalystActivity:2022088] protein-lysine 6-oxidase activity of Lysyl oxidases:Cu2+ [extracellular region]
category	transition
compartment	[Compartment:984] extracellular region
created	[InstanceEdit:2002388] Jupe, S, 2011-11-21
dbId	2002466
displayName	Formation of allysine by LOX
edited	[InstanceEdit:2580335] Jupe, S, 2012-11-12
eventOf	[Pathway:R-HSA-2243919] Crosslinking of collagen fibrils - Homo sapiens
followingEvent	[Reaction:R-HSA-2243931] Formation of dehydro-lysinonorleucine cross-links - Homo sapiens [Reaction:R-HSA-2395257] Formation of dehydro-hydroxylysino-norleucine cross-links - Homo sapiens
input	2 × [Polymer:R-HSA-1474201] Collagen type I fibril [extracellular region] [SimpleEntity:R-ALL-109276] H2O [extracellular region] [SimpleEntity:R-ALL-352327] O2 [extracellular region]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:2022131] The cross-linking of collagen and elastin: enzymatic conversion of lysine in peptide linkage to alpha-aminoadipic-delta-semialdehyde (allysine) by an extract from bone
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Formation of allysine by LOX
output	[Polymer:R-HSA-2228714] Collagen type I fibril with allysines [extracellular region] [SimpleEntity:R-ALL-351629] H2O2 [extracellular region] [SimpleEntity:R-ALL-2022135] NH3 [extracellular region]
precedingEvent	[Reaction:R-HSA-2022141] Prolysyl oxidase activation - Homo sapiens
releaseDate	2012-12-04
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:2514774] Kalamajski, Sebastian, 2012-10-08 [InstanceEdit:2514808] Raleigh, Stuart, 2012-10-08 [InstanceEdit:2588541] Ricard-Blum, Sylvie, 2012-11-19
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-2002466
summation	[Summation:2395276] Lysine residues can be converted to allysine by lysyl oxidas...

Referrals

(hasEvent)	[Pathway:R-HSA-2243919] Crosslinking of collagen fibrils
(precedingEvent)	[Reaction:R-HSA-2243931] Formation of dehydro-lysinonorleucine cross-links [Reaction:R-HSA-2395257] Formation of dehydro-hydroxylysino-norleucine cross-links

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