Reactome | HLA-C group-I-interacting KIRs [plasma membrane]

Schema > DefinedSet > Entries

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-HSA-198909] HLA-C group 1 interacting with KIR2DL2/3 [plasma membrane] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-198958] KIR2DL2/3 interacting with HLA-C group 1 (Cw4) - Homo sapiens
created	[InstanceEdit:199544] de Bono, B, 2007-07-11 12:30:56
dbId	199540
displayName	HLA-C group-I-interacting KIRs [plasma membrane]
hasMember	[EntityWithAccessionedSequence:R-HSA-199532] KIR2DL2 [plasma membrane] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-3006532] KIR2DL3 [plasma membrane] - Homo sapiens
inDisease	false
literatureReference	[LiteratureReference:199529] The KIR gene family: life in the fast lane of evolution [LiteratureReference:199545] Amino acid substitutions can influence the natural killer (NK)-mediated recognition of HLA-C molecules. Role of serine-77 and lysine-80 in the target cell protection from lysis mediated by "group 2" or "group 1" NK clones.
maxDepth	2
modified	[InstanceEdit:3006533] Jupe, S, 2013-01-30
name	HLA-C group-I-interacting KIRs
schemaClass	DefinedSet
species	[Species:48887] Homo sapiens
stId	R-HSA-199540
updateTrackers	[UpdateTracker:9874947] Update Tracker - [DefinedSet:199540] HLA-C group-I-interacting KIRs [plasma membrane] - v44:[add_removeHasMember]

(updatedInstance)	[UpdateTracker:9874947] Update Tracker - [DefinedSet:199540] HLA-C group-I-interacting KIRs [plasma membrane] - v44:[add_removeHasMember]
(hasComponent)	[Complex:R-HSA-198909] HLA-C group 1 interacting with KIR2DL2/3 [plasma membrane]
(input)	[Reaction:R-HSA-198958] KIR2DL2/3 interacting with HLA-C group 1 (Cw4)