Reactome | RNA polymerase III transcribes microbial dsDNA to dsRNA

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RNA polymerase III transcribes microbial dsDNA to dsRNA Show undefined attributes

authored	[InstanceEdit:2396013] Shamovsky, V, 2012-07-09
catalystActivity	[CatalystActivity:1964475] DNA-directed RNA polymerase activity of RNA Polymerase III Holoenzyme [cytosol]
category	omitted
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:1964487] Shamovsky, V, 2011-11-04
dbId	1964482
displayName	RNA polymerase III transcribes microbial dsDNA to dsRNA
edited	[InstanceEdit:3465604] Shamovsky, V, 2013-05-17
eventOf	[Pathway:R-HSA-1834949] Cytosolic sensors of pathogen-associated DNA - Homo sapiens
followingEvent	[Reaction:R-HSA-168935] viral dsRNA binds DDX58 - Homo sapiens
input	[DefinedSet:R-NUL-9013853] Pol-III ligands [cytosol]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:1964486] RNA polymerase III detects cytosolic DNA and induces type I interferons through the RIG-I pathway [LiteratureReference:1964479] RIG-I-dependent sensing of poly(dA:dT) through the induction of an RNA polymerase III-transcribed RNA intermediate
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	RNA polymerase III transcribes microbial dsDNA to dsRNA
output	[OtherEntity:R-ALL-1964477] 5'-ppp-AU-rich dsRNA [cytosol]
relatedSpecies	[Species:9013854] Human gammaherpesvirus 4 [Species:5689680] Human herpesvirus 1 [Species:9013851] Legionella pneumophila
releaseDate	2013-06-11
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:3110284] D'Eustachio, P, 2013-02-11 [InstanceEdit:3597627] Jin, Lei, 2013-05-21 [InstanceEdit:3597624] Wu, Jiaxi, 2013-05-21
schemaClass	BlackBoxEvent
species	[Species:48887] Homo sapiens
stId	R-HSA-1964482
summation	[Summation:1964476] RNA polymerase III (POL III) was reported to sense and trans...
updateTrackers	[UpdateTracker:9780862] Update Tracker - [BlackBoxEvent:1964482] RNA polymerase III transcribes microbial dsDNA to dsRNA - v62:[add_removeInput]

Referrals

(updatedInstance)	[UpdateTracker:9780862] Update Tracker - [BlackBoxEvent:1964482] RNA polymerase III transcribes microbial dsDNA to dsRNA - v62:[add_removeInput]
(hasEvent)	[Pathway:R-HSA-1834949] Cytosolic sensors of pathogen-associated DNA
(precedingEvent)	[Reaction:R-HSA-168935] viral dsRNA binds DDX58

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