Reactome | Binding of M1 to vRNP

Schema > Reaction > Entries

authored	[InstanceEdit:193029] Bortz, E, Garcia-Sastre, A, 2007-02-12 19:39:05
category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:192697] Gillespie, ME, 2007-02-07 04:51:41
dbId	192746
disease	[Disease:1660558] influenza
displayName	Binding of M1 to vRNP
eventOf	[Pathway:R-HSA-168330] Viral RNP Complexes in the Host Cell Nucleus - Homo sapiens
followingEvent	[Reaction:R-HSA-168893] Binding of NEP/NS2 to vRNP:M1 - Homo sapiens
input	8 × [EntityWithAccessionedSequence:R-FLU-186959] M1 [nucleoplasm] [Complex:R-FLU-192922] vRNP destined for Export [nucleoplasm]
isInDisease	true
isInferred	false
literatureReference	[LiteratureReference:192881] In vitro dissection of the membrane and RNP binding activities of influenza virus M1 protein
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Binding of M1 to vRNP
output	[Complex:R-FLU-192906] vRNP:M1 for Export [nucleoplasm]
precedingEvent	[Reaction:R-HSA-192677] Newly synthesized vRNP for export - Homo sapiens
regulatedBy	[NegativeRegulation:R-HSA-192889] Negative regulation by 'HSPA1A [nucleoplasm]'
relatedSpecies	[Species:9031716] Influenza A virus
releaseDate	2006-01-23
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:193030] Squires, B, 2007-02-12 19:39:22
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-192746
summation	[Summation:192671] M1 protein binds to viral RNP through its C-terminal domain ...

(precedingEvent)	[Reaction:R-HSA-168893] Binding of NEP/NS2 to vRNP:M1
(hasEvent)	[Pathway:R-HSA-168330] Viral RNP Complexes in the Host Cell Nucleus

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