Reactome | Isomerization of 25(R) THCA-CoA to 25(S) THCA-CoA

Schema > Reaction > Entries

Isomerization of 25(R) THCA-CoA to 25(S) THCA-CoA Show undefined attributes

authored	[InstanceEdit:191331] Jassal, Bijay, 2007-01-19
catalystActivity	[CatalystActivity:191973] alpha-methylacyl-CoA racemase activity of AMACR [peroxisomal matrix]
category	transition
compartment	[Compartment:17951] peroxisomal matrix
created	[InstanceEdit:191989] Jassal, Bijay, 2007-01-26
crossReference	[DatabaseIdentifier:12668336] RHEA:40456
dbId	192056
displayName	Isomerization of 25(R) THCA-CoA to 25(S) THCA-CoA
edited	[InstanceEdit:193475] D'Eustachio, P, 2007-02-17 19:40:28
eventOf	[Pathway:R-HSA-193368] Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol - Homo sapiens
followingEvent	[Reaction:R-HSA-192335] 25(S) THCA-CoA is dehydrogenated to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) - Homo sapiens
input	[SimpleEntity:R-ALL-192308] 25(R) THCA-CoA [peroxisomal matrix]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:192112] Purification and characterization of an alpha-methylacyl-CoA racemase from human liver [LiteratureReference:192185] Mitochondrial and peroxisomal targeting of 2-methylacyl-CoA racemase in humans [LiteratureReference:193502] Mutations in the gene encoding peroxisomal alpha-methylacyl-CoA racemase cause adult-onset sensory motor neuropathy
maxDepth	1
modified	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
name	Isomerization of 25(R) THCA-CoA to 25(S) THCA-CoA 25(R) THCA-CoA => 25(S) THCA-CoA
orthologousEvent	[Reaction:R-CEL-192056] Isomerization of 25(R) THCA-CoA to 25(S) THCA-CoA - Caenorhabditis elegans [Reaction:R-DME-192056] Isomerization of 25(R) THCA-CoA to 25(S) THCA-CoA - Drosophila melanogaster [Reaction:R-GGA-192056] Isomerization of 25(R) THCA-CoA to 25(S) THCA-CoA - Gallus gallus [Reaction:R-XTR-192056] Isomerization of 25(R) THCA-CoA to 25(S) THCA-CoA - Xenopus tropicalis [Reaction:R-DRE-192056] Isomerization of 25(R) THCA-CoA to 25(S) THCA-CoA - Danio rerio [Reaction:R-BTA-192056] Isomerization of 25(R) THCA-CoA to 25(S) THCA-CoA - Bos taurus [Reaction:R-RNO-192056] Isomerization of 25(R) THCA-CoA to 25(S) THCA-CoA - Rattus norvegicus [Reaction:R-MMU-192056] Isomerization of 25(R) THCA-CoA to 25(S) THCA-CoA - Mus musculus
output	[SimpleEntity:R-ALL-192316] 25(S) THCA-CoA [peroxisomal matrix]
precedingEvent	[BlackBoxEvent:R-HSA-192325] 25(R) THCA-CoA is translocated from the cytosol to the peroxisome - Homo sapiens
releaseDate	2007-05-15
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:197117] D'Eustachio, P, 2007-04-30 14:43:26
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-192056
summation	[Summation:192099] The isomerization of 25(R) THCA-CoA to 25(S) THCA-CoA, catal...

Referrals

(hasEvent)	[Pathway:R-HSA-193368] Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
(precedingEvent)	[Reaction:R-HSA-192335] 25(S) THCA-CoA is dehydrogenated to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA)