Reactome | NOTCH2 gene transcription

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NOTCH2 gene transcription Show undefined attributes

authored	[InstanceEdit:2121208] Egan, SE, Orlic-Milacic, M, 2011-11-14
category	omitted
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:1912405] Orlic-Milacic, M, 2011-11-01
dbId	1912407
displayName	NOTCH2 gene transcription
edited	[InstanceEdit:2106576] Orlic-Milacic, M, 2012-02-10 [InstanceEdit:2098673] D'Eustachio, P, 2012-02-06
eventOf	[Pathway:R-HSA-1912408] Pre-NOTCH Transcription and Translation - Homo sapiens
followingEvent	[Reaction:R-HSA-1912367] MIR34 microRNAs bind 3'UTR of NOTCH2 mRNA - Homo sapiens [BlackBoxEvent:R-HSA-1912413] NOTCH2 mRNA translation controlled by miRNAs - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-1911484] NOTCH2 gene [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:2025782] The human NOTCH1, 2, and 3 genes are located at chromosome positions 9q34, 1p13-p11, and 19p13.2-p13.1 in regions of neoplasia-associated translocation [LiteratureReference:2025785] Notch-1 and Notch-2 exhibit unique patterns of expression in human B-lineage cells [LiteratureReference:2025784] NOTCH2 mutations cause Alagille syndrome, a heterogeneous disorder of the notch signaling pathway
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	NOTCH2 gene transcription
output	[EntityWithAccessionedSequence:R-HSA-1911477] NOTCH2 mRNA [cytosol]
releaseDate	2012-03-13
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:2121207] Haw, R, 2012-02-06
schemaClass	BlackBoxEvent
species	[Species:48887] Homo sapiens
stId	R-HSA-1912407
summation	[Summation:2025780] The NOTCH2 gene maps to human chromosome 1. NOTCH2 gene expr...

Referrals

(precedingEvent)	[Reaction:R-HSA-1912367] MIR34 microRNAs bind 3'UTR of NOTCH2 mRNA [BlackBoxEvent:R-HSA-1912413] NOTCH2 mRNA translation controlled by miRNAs
(hasEvent)	[Pathway:R-HSA-1912408] Pre-NOTCH Transcription and Translation

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