Reactome | maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase)

Schema > Reaction > Entries

maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase) Show undefined attributes

authored	[InstanceEdit:189111] D'Eustachio, P, 2006-11-03 14:36:07
catalystActivity	[CatalystActivity:189007] alpha-1,4-glucosidase activity of sucrase-isomaltase dimer [plasma membrane]
catalystActivityReference	[CatalystActivityReference:9643760] alpha-1,4-glucosidase activity of sucrase-isomaltase dimer [plasma membrane] Structural basis for substrate selectivity in human maltase-glucoamylase and sucrase-isomaltase N-terminal domains
category	transition
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:191105] D'Eustachio, P, 2007-01-18 18:40:09
crossReference	[DatabaseIdentifier:9966219] RHEA:27971
dbId	191101
diseaseReaction	[FailedReaction:R-HSA-5659899] Defective SI does not hydrolyze maltotriose - Homo sapiens
displayName	maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase)
eventOf	[Pathway:R-HSA-189085] Digestion of dietary carbohydrate - Homo sapiens
followingEvent	[Reaction:R-HSA-8932955] SLC5A1 cotransports Glc,Gal with Na+ from extracellular region to cytosol - Homo sapiens [Reaction:R-HSA-189102] maltose + H2O => 2 D-glucose (maltase-glucoamylase) - Homo sapiens [Reaction:R-HSA-191108] maltose + H2O => 2 D-glucose (sucrase-isomaltase) - Homo sapiens
input	[SimpleEntity:R-ALL-109276] H2O [extracellular region] [SimpleEntity:R-ALL-191103] maltotriose [extracellular region]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:188987] Expression and intracellular transport of microvillus membrane hydrolases in human intestinal epithelial cells [LiteratureReference:189072] The maltase-glucoamylase gene: common ancestry to sucrase-isomaltase with complementary starch digestion activities
maxDepth	1
modified	[InstanceEdit:11051501] Weiser, Joel, 2026-03-16
name	maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase) Digestion of maltotriose by sucrase-isomaltase to yield maltose and glucose
orthologousEvent	[Reaction:R-SPO-191101] maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase) - Schizosaccharomyces pombe [Reaction:R-DDI-191101] maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase) - Dictyostelium discoideum [Reaction:R-CEL-191101] maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase) - Caenorhabditis elegans [Reaction:R-GGA-191101] maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase) - Gallus gallus [Reaction:R-XTR-191101] maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase) - Xenopus tropicalis [Reaction:R-SSC-191101] maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase) - Sus scrofa [Reaction:R-BTA-191101] maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase) - Bos taurus [Reaction:R-CFA-191101] maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase) - Canis familiaris [Reaction:R-RNO-191101] maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase) - Rattus norvegicus [Reaction:R-MMU-191101] maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase) - Mus musculus
output	[SimpleEntity:R-ALL-70115] Glc [extracellular region] [SimpleEntity:R-ALL-188986] Mal [extracellular region]
precedingEvent	[Reaction:R-HSA-188979] Digestion of linear starch (amylose) by extracellular amylase - Homo sapiens [Reaction:R-HSA-191114] Digestion of branched starch (amylopectin) by extracellular amylase - Homo sapiens [Reaction:R-HSA-189053] Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose - Homo sapiens
releaseDate	2007-02-20
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:191109] Nichols, BL, 2007-01-15 21:51:24
revised	[InstanceEdit:191106] D'Eustachio, P, 2007-01-18 16:51:37
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-191101
summation	[Summation:189070] Maltotriose is representative of linear glucose oligomers co...
updateTrackers	[UpdateTracker:9785252] Update Tracker - [Reaction:191101] maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase) - v52:[modifyText, removeLiteratureReference]

Referrals

(updatedInstance)	[UpdateTracker:9785252] Update Tracker - [Reaction:191101] maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase) - v52:[modifyText, removeLiteratureReference]
(normalReaction)	[FailedReaction:R-HSA-5659899] Defective SI does not hydrolyze maltotriose
(precedingEvent)	[Reaction:R-HSA-8932955] SLC5A1 cotransports Glc,Gal with Na+ from extracellular region to cytosol [Reaction:R-HSA-189102] maltose + H2O => 2 D-glucose (maltase-glucoamylase) [Reaction:R-HSA-191108] maltose + H2O => 2 D-glucose (sucrase-isomaltase)
(hasEvent)	[Pathway:R-HSA-189085] Digestion of dietary carbohydrate

Cite Us!