maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase)

Stable Identifier
R-HSA-191101
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Synonyms
Digestion of maltotriose by sucrase-isomaltase to yield maltose and glucose
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Maltotriose is representative of linear glucose oligomers containing more than two residues. The 1-4 linkages of extracellular maltotriose are hydrolyzed to yield maltose and glucose in a reaction catalyzed by the exoglucosidase activity of sucrase-isomaltase (Nichols et al. 1998). In the body, this enzyme is found as a heterodimer on the external face of enterocytes in microvilli of the small intestine (Hauri et al. 1985), and acts on maltotriose derived directly from the diet and from the hydrolysis of starch, although with lower activity than maltase-glucoamylase.

Literature References
PubMed ID Title Journal Year
12547908 The maltase-glucoamylase gene: common ancestry to sucrase-isomaltase with complementary starch digestion activities

Nichols, BL, Avery, S, Sen, P, Swallow, DM, Hahn, D, Sterchi, EE

Proc Natl Acad Sci U S A 2003
3897250 Expression and intracellular transport of microvillus membrane hydrolases in human intestinal epithelial cells

Hauri, HP, Sterchi, EE, Bienz, D, Fransen, JA, Marxer, A

J Cell Biol 1985
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
alpha-1,4-glucosidase activity of sucrase-isomaltase dimer [plasma membrane]
Physical Entity
Activity
Orthologous Events
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