Reactome | FGFR1c homodimer [plasma membrane]

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FGFR1c homodimer [plasma membrane] Show undefined attributes

catalystActivities	[CatalystActivity:5654541] protein tyrosine kinase activity of FGFR1c homodimer [plasma membrane]
compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-HSA-419028] NCAM1:FGFR-1 [plasma membrane] - Homo sapiens [Complex:R-HSA-190218] FGF23 bound to Klotho and FGFR1c [plasma membrane] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-5654545] Ligand-independent phosphorylation of overexpressed FGFR1c - Homo sapiens [Reaction:R-HSA-419033] NCAM1 binds FGFR-1 - Homo sapiens
created	[InstanceEdit:190229] de Bono, B, 2006-12-18 13:54:50
dbId	190222
deleted	[Deleted:192394] Deletion of instance: 190219
displayName	FGFR1c homodimer [plasma membrane]
hasComponent	2 × [EntityWithAccessionedSequence:R-HSA-189897] FGFR1c [plasma membrane]
inDisease	false
inferredTo	[Complex:R-MMU-420360] FGFR-1 homodimer [plasma membrane] - Mus musculus [Complex:R-RNO-190222] FGFR1c homodimer [plasma membrane] - Rattus norvegicus [Complex:R-CFA-190222] FGFR1c homodimer [plasma membrane] - Canis familiaris [Complex:R-BTA-190222] FGFR1c homodimer [plasma membrane] - Bos taurus [Complex:R-SSC-190222] FGFR1c homodimer [plasma membrane] - Sus scrofa [Complex:R-DRE-190222] FGFR1c homodimer [plasma membrane] - Danio rerio [Complex:R-XTR-190222] FGFR1c homodimer [plasma membrane] - Xenopus tropicalis [Complex:R-GGA-190222] FGFR1c homodimer [plasma membrane] - Gallus gallus [Complex:R-DME-190222] FGFR1c homodimer [plasma membrane] - Drosophila melanogaster [Complex:R-CEL-190222] FGFR1c homodimer [plasma membrane] - Caenorhabditis elegans
maxDepth	2
memberOf	[DefinedSet:R-HSA-1982053] Overexpressed FGFR1 homodimers [plasma membrane] - Homo sapiens
modified	[InstanceEdit:190308] de Bono, B, 2007-01-02 10:06:19
name	FGFR1c homodimer
producedByEvent	[Reaction:R-HSA-5654544] Ligand-independent dimerization of overexpressed FGFR1c - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-190222

Referrals

(replacementInstances)	[Deleted:192394] Deletion of instance: 190219
(hasMember)	[DefinedSet:R-HSA-1982053] Overexpressed FGFR1 homodimers [plasma membrane]
(input)	[Reaction:R-HSA-5654545] Ligand-independent phosphorylation of overexpressed FGFR1c [Reaction:R-HSA-419033] NCAM1 binds FGFR-1
(diseaseEntity)	[EntityFunctionalStatus:5654546] gain_of_function of FGFR1c homodimer [plasma membrane]
(physicalEntity)	[CatalystActivity:5654541] protein tyrosine kinase activity of FGFR1c homodimer [plasma membrane]
(output)	[Reaction:R-HSA-5654544] Ligand-independent dimerization of overexpressed FGFR1c
(hasComponent)	[Complex:R-HSA-419028] NCAM1:FGFR-1 [plasma membrane] [Complex:R-HSA-190233] FGFR1c homodimer bound to FGF [plasma membrane] [Complex:R-HSA-190218] FGF23 bound to Klotho and FGFR1c [plasma membrane]

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