Reactome | The signal peptide is excised from beta-NGF pre-pro-precursor

Schema > Reaction > Entries

authored	[InstanceEdit:188342] Nasi, Sergio, Annibali, D, 2006-10-10
category	transition
compartment	[Compartment:17957] endoplasmic reticulum lumen
created	[InstanceEdit:187008] Jassal, Bijay, 2006-09-07
dbId	187045
displayName	The signal peptide is excised from beta-NGF pre-pro-precursor
edited	[InstanceEdit:188340] Jassal, Bijay, 2006-10-10
eventOf	[Pathway:R-HSA-167060] NGF processing - Homo sapiens
followingEvent	[Reaction:R-HSA-167047] pro-beta-NGF dimerizes - Homo sapiens
inferredFrom	[Reaction:R-MMU-181788] The signal peptide is excised from pre-pro-NGF - Mus musculus
input	[EntityWithAccessionedSequence:R-HSA-187026] NGF(1-241) [endoplasmic reticulum lumen]
isInDisease	false
isInferred	true
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	The signal peptide is excised from beta-NGF pre-pro-precursor
output	[EntityWithAccessionedSequence:R-HSA-187047] NGF(19-241) [endoplasmic reticulum lumen]
releaseDate	2007-12-11
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:202668] Greene, LA, 2007-11-08 15:39:37
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-187045
summation	[Summation:167040] Pre-pro- precursors of the neurotrophins NGF, BDNF, NT-3, NT...

(hasEvent)	[Pathway:R-HSA-167060] NGF processing
(precedingEvent)	[Reaction:R-HSA-167047] pro-beta-NGF dimerizes
(inferredTo)	[Reaction:R-MMU-181788] The signal peptide is excised from pre-pro-NGF

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