Reactome | Pro-beta-NGF and mature beta-NGF are secreted

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Pro-beta-NGF and mature beta-NGF are secreted Show undefined attributes

authored	[InstanceEdit:188342] Nasi, Sergio, Annibali, D, 2006-10-10
category	transition
compartment	[Compartment:984] extracellular region [Compartment:17963] Golgi lumen
created	[InstanceEdit:187008] Jassal, Bijay, 2006-09-07
dbId	187035
displayName	Pro-beta-NGF and mature beta-NGF are secreted
edited	[InstanceEdit:188340] Jassal, Bijay, 2006-10-10
eventOf	[Pathway:R-HSA-167060] NGF processing - Homo sapiens
input	[Complex:R-HSA-187017] mature beta-NGF homodimer [Golgi lumen] [Complex:R-HSA-187028] pro-beta-NGF homodimer [Golgi lumen]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:189671] Neurotrophin secretion: current facts and future prospects
maxDepth	1
modified	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
name	Pro-beta-NGF and mature beta-NGF are secreted
orthologousEvent	[Reaction:R-DRE-187035] Pro-beta-NGF and mature beta-NGF are secreted - Danio rerio [Reaction:R-GGA-187035] Pro-beta-NGF and mature beta-NGF are secreted - Gallus gallus [Reaction:R-XTR-187035] Pro-beta-NGF and mature beta-NGF are secreted - Xenopus tropicalis [Reaction:R-SSC-187035] Pro-beta-NGF and mature beta-NGF are secreted - Sus scrofa [Reaction:R-BTA-187035] Pro-beta-NGF and mature beta-NGF are secreted - Bos taurus [Reaction:R-CFA-187035] Pro-beta-NGF and mature beta-NGF are secreted - Canis familiaris [Reaction:R-RNO-187035] Pro-beta-NGF and mature beta-NGF are secreted - Rattus norvegicus [Reaction:R-MMU-187035] Pro-beta-NGF and mature beta-NGF are secreted - Mus musculus
output	[Complex:R-HSA-187031] mature beta-NGF homodimer [extracellular region] [Complex:R-HSA-187029] pro-beta-NGF homodimer [extracellular region]
precedingEvent	[Reaction:R-HSA-187020] Part of pro-beta-NGF is processed to mature beta-NGF - Homo sapiens [Reaction:R-HSA-167014] pro-beta-NGF homodimer transits to the golgi apparatus - Homo sapiens
releaseDate	2007-12-11
reviewStatus	[ReviewStatus:9821382] five stars
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-187035
summation	[Summation:187050] Both mature neurotrophin and pro-neurotrophin are released e...

Referrals

(hasEvent)

[Pathway:R-HSA-167060] NGF processing