Reactome | IP6 transports from the cytosol to the ER lumen

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IP6 transports from the cytosol to the ER lumen Show undefined attributes

authored	[InstanceEdit:1855226] Williams, MG, 2011-10-28
catalystActivity	[CatalystActivity:9954154] myo-inositol transmembrane transporter activity of unknown PI transporter [endoplasmic reticulum membrane]
category	transition
compartment	[Compartment:70101] cytosol [Compartment:17957] endoplasmic reticulum lumen
created	[InstanceEdit:1855226] Williams, MG, 2011-10-28
dbId	1855164
displayName	IP6 transports from the cytosol to the ER lumen
edited	[InstanceEdit:1855226] Williams, MG, 2011-10-28
eventOf	[Pathway:R-HSA-1855184] IPs transport between cytosol and ER lumen - Homo sapiens
followingEvent	[Reaction:R-HSA-1855225] IP6 is dephosphorylated to I(1,2,4,5,6)P5 by MINPP1 in the ER lumen - Homo sapiens
input	[SimpleEntity:R-ALL-1629770] IP6 [cytosol]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:1889863] The human and rat forms of multiple inositol polyphosphate phosphatase: functional homology with a histidine acid phosphatase up-regulated during endochondral ossification
maxDepth	1
modified	[InstanceEdit:9963234] D'Eustachio, Peter, 2025-08-13
name	IP6 transports from the cytosol to the ER lumen
output	[SimpleEntity:R-ALL-2024018] IP6 [endoplasmic reticulum lumen]
precedingEvent	[Reaction:R-HSA-1855179] I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK in the cytosol - Homo sapiens [Reaction:R-HSA-1855198] 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol - Homo sapiens [Reaction:R-HSA-2023971] 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol - Homo sapiens
previousReviewStatus	[ReviewStatus:9821385] four stars
releaseDate	2012-12-04
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:2562610] Wundenberg, Torsten, 2012-11-06 [InstanceEdit:9963235] Hill, David P, 2025-08-13
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-1855164
summation	[Summation:2024011] 1,2,3,4,5,6-hexakisphosphate (IP6) translocates from the cyt...
updateTrackers	[UpdateTracker:9964650] Update Tracker - [Reaction:1855164] IP6 transports from the cytosol to the ER lumen - v94:[removeCatalystActivity]

Referrals

(updatedInstance)	[UpdateTracker:9964650] Update Tracker - [Reaction:1855164] IP6 transports from the cytosol to the ER lumen - v94:[removeCatalystActivity]
(hasEvent)	[Pathway:R-HSA-1855184] IPs transport between cytosol and ER lumen
(precedingEvent)	[Reaction:R-HSA-1855225] IP6 is dephosphorylated to I(1,2,4,5,6)P5 by MINPP1 in the ER lumen

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