Reactome | Disassembly of the Rev-importin beta-B23:Ran-GTP complex

Schema > Reaction > Entries

Disassembly of the Rev-importin beta-B23:Ran-GTP complex Show undefined attributes

authored	[InstanceEdit:180938] Matthews, L, 2006-06-08 06:14:23
category	dissociation
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:180726] Matthews, L, 2006-06-02 09:30:33
crossReference	[DatabaseIdentifier:12020765] Mondo:0005109
dbId	180736
disease	[Disease:1660559] Human immunodeficiency virus infectious disease
displayName	Disassembly of the Rev-importin beta-B23:Ran-GTP complex
edited	[InstanceEdit:192363] Matthews, L, 2007-01-31 22:42:03
eventOf	[Pathway:R-HSA-180746] Nuclear import of Rev protein - Homo sapiens
followingEvent	[Reaction:R-HSA-165027] Rev molecules assemble onto the RRE RNA sequence through their ARM sequence - Homo sapiens
input	[Complex:R-HSA-180712] Rev:importin-beta:B23:Ran-GTP complex [nucleoplasm]
isInDisease	true
isInferred	false
literatureReference	[LiteratureReference:180839] Interactions between HIV Rev and nuclear import and export factors: the Rev nuclear localisation signal mediates specific binding to human importin-beta
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Disassembly of the Rev-importin beta-B23:Ran-GTP complex
orthologousEvent	[Reaction:R-HSA-180732] Translocation of Rev:importin-beta:B23 to the nucleus - Homo sapiens
output	[Complex:R-HSA-180719] Importin-beta:Ran GTP complex [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-606320] NPM1 [nucleoplasm] [Polymer:R-HIV-165542] Rev-multimer [nucleoplasm]
precedingEvent	[Reaction:R-HSA-180732] Translocation of Rev:importin-beta:B23 to the nucleus - Homo sapiens
relatedSpecies	[Species:164493] Human immunodeficiency virus 1
releaseDate	2007-02-20
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:192365] Kumar, A, 2007-01-31 22:47:49
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-180736
summation	[Summation:180852] The association of importin-beta with Ran-GTP causes the dis...
updateTrackers	[UpdateTracker:9787577] Update Tracker - [Reaction:180736] Disassembly of the Rev-importin beta-B23:Ran-GTP complex - v44:[add_removeOutput] [UpdateTracker:9782090] Update Tracker - [Reaction:180736] Disassembly of the Rev-importin beta-B23:Ran-GTP complex - v59:[modifyText] [UpdateTracker:9789879] Update Tracker - [Reaction:180736] Disassembly of the Rev-importin beta-B23:Ran-GTP complex - v37:[modifyText]

Referrals

(updatedInstance)	[UpdateTracker:9787577] Update Tracker - [Reaction:180736] Disassembly of the Rev-importin beta-B23:Ran-GTP complex - v44:[add_removeOutput] [UpdateTracker:9782090] Update Tracker - [Reaction:180736] Disassembly of the Rev-importin beta-B23:Ran-GTP complex - v59:[modifyText] [UpdateTracker:9789879] Update Tracker - [Reaction:180736] Disassembly of the Rev-importin beta-B23:Ran-GTP complex - v37:[modifyText]
(hasEvent)	[Pathway:R-HSA-180746] Nuclear import of Rev protein
(precedingEvent)	[Reaction:R-HSA-165027] Rev molecules assemble onto the RRE RNA sequence through their ARM sequence