Reactome | KPNB1 [cytosol]

Schema > EntityWithAccessionedSequence > Entries

KPNB1 [cytosol] Show undefined attributes

catalystActivities	[CatalystActivity:9959902] nuclear import signal receptor activity of KPNB1 [cytosol]
compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-HSA-180707] Importin beta-1:Rev multimer complex [cytosol] - Homo sapiens [Complex:R-HSA-2065556] SREBP1A,1C,2:Importin beta-1 [cytosol] - Homo sapiens [Complex:R-HSA-9706975] KPNA2:KPNB1:6 [endoplasmic reticulum-Golgi intermediate compartment membrane] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-9710963] p-STAT1dimer:KPNA1 binds KPNB1 - Homo sapiens [Reaction:R-HSA-9710963] p-STAT1dimer:KPNA1 binds KPNB1 - Homo sapiens [Reaction:R-HSA-2065550] SREBP1A,1C,2 binds Importin beta-1 - Homo sapiens [Reaction:R-HSA-9706977] 6:KPNA2 binds KPNB1 - Homo sapiens [Reaction:R-HSA-180709] Association of multimerized Rev with beta-importin - Homo sapiens [Reaction:R-HSA-9624798] LBR binds KPNB1 - Homo sapiens [Reaction:R-HSA-168317] Recruitment of Karyopherin Beta to form a Trimeric Complex - Homo sapiens
created	[InstanceEdit:180726] Matthews, L, 2006-06-02 09:30:33
dbId	180733
deleted	[Deleted:205149] Deletion of instance: 188841
displayName	KPNB1 [cytosol]
endCoordinate	876
inDisease	false
inferredTo	[EntityWithAccessionedSequence:R-MMU-2065541] Importin subunit beta-1 [cytosol] - Mus musculus [EntityWithAccessionedSequence:R-RNO-180733] Kpnb1 [cytosol] - Rattus norvegicus [GenomeEncodedEntity:R-CFA-180733] Ghost homologue of KPNB1 [cytosol] - Canis familiaris [EntityWithAccessionedSequence:R-BTA-180733] KPNB1 [cytosol] - Bos taurus [EntityWithAccessionedSequence:R-SSC-180733] KPNB1 [cytosol] - Sus scrofa [EntityWithAccessionedSequence:R-DRE-180733] kpnb1 [cytosol] - Danio rerio [EntityWithAccessionedSequence:R-XTR-180733] kpnb1 [cytosol] - Xenopus tropicalis [EntityWithAccessionedSequence:R-GGA-180733] KPNB1 [cytosol] - Gallus gallus [EntityWithAccessionedSequence:R-DME-180733] Fs(2)Ket [cytosol] - Drosophila melanogaster [EntityWithAccessionedSequence:R-CEL-180733] imb-1 [cytosol] - Caenorhabditis elegans [EntityWithAccessionedSequence:R-SPO-180733] kap95 [cytosol] - Schizosaccharomyces pombe [EntityWithAccessionedSequence:R-SCE-180733] KAP95 [cytosol] - Saccharomyces cerevisiae [EntityWithAccessionedSequence:R-PFA-180733] KPNB1 [cytosol] - Plasmodium falciparum
maxDepth	1
memberOf	[DefinedSet:R-HSA-9615955] KPNB1,TNPO1 [cytosol] - Homo sapiens
modified	[InstanceEdit:3632907] Wu, G, 2013-05-28
name	KPNB1 Importin beta-1 Karyopherin beta
positivelyRegulates	[PositiveRegulation:9832894] Positive regulation by 'KPNB1 [cytosol]'
producedByEvent	[Reaction:R-HSA-9924266] Ivermectin binds importin - Homo sapiens
referenceEntity	[ReferenceGeneProduct:uniprot:Q14974] UniProt:Q14974 KPNB1
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-180733
startCoordinate	1
updateTrackers	[UpdateTracker:9866641] Update Tracker - [EntityWithAccessionedSequence:180733] KPNB1 [cytosol] - v24:[addName] [UpdateTracker:9876654] Update Tracker - [EntityWithAccessionedSequence:180733] KPNB1 [cytosol] - v44:[modifyEndCoordinate] [UpdateTracker:9881566] Update Tracker - [EntityWithAccessionedSequence:180733] KPNB1 [cytosol] - v45:[addName]

Referrals

(updatedInstance)	[UpdateTracker:9866641] Update Tracker - [EntityWithAccessionedSequence:180733] KPNB1 [cytosol] - v24:[addName] [UpdateTracker:9876654] Update Tracker - [EntityWithAccessionedSequence:180733] KPNB1 [cytosol] - v44:[modifyEndCoordinate] [UpdateTracker:9881566] Update Tracker - [EntityWithAccessionedSequence:180733] KPNB1 [cytosol] - v45:[addName]
(replacementInstances)	[Deleted:205149] Deletion of instance: 188841
(hasComponent)	[Complex:R-HSA-2065556] SREBP1A,1C,2:Importin beta-1 [cytosol] [Complex:R-HSA-9954401] IMP?/?1 [cytosol] [Complex:R-HSA-9706975] KPNA2:KPNB1:6 [endoplasmic reticulum-Golgi intermediate compartment membrane] [Complex:R-HSA-180707] Importin beta-1:Rev multimer complex [cytosol] [Complex:R-HSA-9624816] p-S71,S86-LBR:KPNB1 [nuclear envelope] [Complex:R-HSA-188853] RNP:Karyopherin alpha:Karyopherin beta complex [cytosol] [Complex:R-HSA-9757480] p-Y701-STAT1:KPNA1:KPNB1 [cytosol] [Complex:R-HSA-9710965] ISGF3:KPNA1:KPNB1 [cytosol] [Complex:R-HSA-350277] importin-alpha:importin-beta [cytosol] [Complex:R-HSA-9734668] KPNA1,KPNA6:KPNB1 [cytosol]
(input)	[Reaction:R-HSA-2065550] SREBP1A,1C,2 binds Importin beta-1 [Reaction:R-HSA-9706977] 6:KPNA2 binds KPNB1 [Reaction:R-HSA-180709] Association of multimerized Rev with beta-importin [Reaction:R-HSA-9624798] LBR binds KPNB1 [Reaction:R-HSA-168317] Recruitment of Karyopherin Beta to form a Trimeric Complex [Reaction:R-HSA-9710963] p-STAT1dimer:KPNA1 binds KPNB1
(physicalEntity)	[CatalystActivity:9959902] nuclear import signal receptor activity of KPNB1 [cytosol]
(regulator)	[PositiveRegulation:9832894] Positive regulation by 'KPNB1 [cytosol]'
(output)	[Reaction:R-HSA-9924266] Ivermectin binds importin
(hasMember)	[DefinedSet:R-HSA-9615955] KPNB1,TNPO1 [cytosol] [DefinedSet:R-HSA-1176060] Importin [cytosol]

Cite Us!