Reactome | Unknown endo-?-galactosidase cleaves keratan chain

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Unknown endo-?-galactosidase cleaves keratan chain Show undefined attributes

authored	[InstanceEdit:1793216] Jassal, B, 2011-10-21
catalystActivity	[CatalystActivity:1793215] beta-galactosidase activity of keratan sulfate 1,4-beta-D-galactosidase [lysosomal lumen]
category	uncertain
compartment	[Compartment:161320] lysosomal lumen
created	[InstanceEdit:1793216] Jassal, B, 2011-10-21
dbId	1793217
displayName	Unknown endo-?-galactosidase cleaves keratan chain
edited	[InstanceEdit:1793216] Jassal, B, 2011-10-21
eventOf	[Pathway:R-HSA-2022857] Keratan sulfate degradation - Homo sapiens
followingEvent	[Reaction:R-HSA-1630304] GALNS oligomer hydrolyses sulfate from Gal6S in keratan sulfate - Homo sapiens
goBiologicalProcess	[GO_BiologicalProcess:11234] keratan sulfate proteoglycan catabolic process
input	[SimpleEntity:R-ALL-1605715] H2O [lysosomal lumen] [DefinedSet:R-HSA-2046191] KSPG(2) [lysosomal lumen]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:1605727] Human small-intestinal beta-galactosidases. Separation and characterization of one lactase and one hetero beta-galactosidase
maxDepth	1
modified	[InstanceEdit:9942322] Stephan, Ralf, 2025-03-14
name	Unknown endo-?-galactosidase cleaves keratan chain Keratan sulfate is cleaved from its proteoglycan by an unknown galactosidase
output	[SimpleEntity:R-ALL-2105007] Gal(S)-GlcNAc(S)-Gal-GlcNAc(S)-Gal [lysosomal lumen] [DefinedSet:R-HSA-2105011] KS core proteins [lysosomal lumen]
precedingEvent	[BlackBoxEvent:R-HSA-2046239] Extracellular KSPG translocates to the lysosome for degradation - Homo sapiens
releaseDate	2012-06-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:2172129] D'Eustachio, P, 2012-03-28
schemaClass	BlackBoxEvent
species	[Species:48887] Homo sapiens
stId	R-HSA-1793217
summation	[Summation:1793228] Keratan sulfate (KS) is cleaved from its KS proteoglycan (KS...
updateTrackers	[UpdateTracker:9953712] Update Tracker - [BlackBoxEvent:1793217] Unknown endo-?-galactosidase cleaves keratan chain - v93:[modifyText]

Referrals

(updatedInstance)	[UpdateTracker:9953712] Update Tracker - [BlackBoxEvent:1793217] Unknown endo-?-galactosidase cleaves keratan chain - v93:[modifyText]
(hasEvent)	[Pathway:R-HSA-2022857] Keratan sulfate degradation
(precedingEvent)	[Reaction:R-HSA-1630304] GALNS oligomer hydrolyses sulfate from Gal6S in keratan sulfate

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