Reactome | Formation of RTC (Reverse Transcription Complex)

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Formation of RTC (Reverse Transcription Complex) Show undefined attributes

authored	[InstanceEdit:177630] Iordanskiy, S, Bukrinsky, Michael, 2006-04-03
category	dissociation
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:173765] Gopinathrao, G, 2006-02-16 23:18:33
dbId	173771
disease	[Disease:1660559] Human immunodeficiency virus infectious disease
displayName	Formation of RTC (Reverse Transcription Complex)
edited	[InstanceEdit:174499] Gopinathrao, G, 2006-02-17 18:35:46
eventOf	[Pathway:R-HSA-162594] Early Phase of HIV Life Cycle - Homo sapiens
followingEvent	[Reaction:R-HSA-164527] Annealing of 3'-end of unwound transfer RNA primer with genomic RNA - Homo sapiens
goBiologicalProcess	[GO_BiologicalProcess:6576] uncoating of virus
input	[Complex:R-HSA-173653] uncoated viral complex [cytosol]
isInDisease	true
isInferred	false
literatureReference	[LiteratureReference:175607] Association of integrase, matrix, and reverse transcriptase antigens of human immunodeficiency virus type 1 with viral nucleic acids following acute infection [LiteratureReference:177580] Intracytoplasmic maturation of the human immunodeficiency virus type 1 reverse transcription complexes determines their capacity to integrate into chromatin [LiteratureReference:175931] Morphologic changes in human immunodeficiency virus type 1 virions secondary to intravirion reverse transcription: evidence indicating that reverse transcription may not take place within the intact viral core [LiteratureReference:175651] Characterization of intracellular reverse transcription complexes of human immunodeficiency virus type 1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Formation of RTC (Reverse Transcription Complex)
output	[DefinedSet:R-HIV-175167] Nucleocapsid [cytosol] [EntityWithAccessionedSequence:R-HIV-173808] other viral genomic RNA [cytosol] [EntityWithAccessionedSequence:R-HIV-175182] PR (Protease) (P04585) protein [cytosol] [Complex:R-HSA-173814] RTC (Reverse Transcription Complex) with RNA template [cytosol]
precedingEvent	[Reaction:R-HSA-173111] Disassembly of viral capsid - Homo sapiens
relatedSpecies	[Species:164493] Human immunodeficiency virus 1
releaseDate	2006-11-14
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:188938] Aiken, C, 2006-10-30 22:04:39
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-173771
summation	[Summation:177585] Reverse transcription complex is a transitory structure wher...

Referrals

(hasEvent)	[Pathway:R-HSA-162594] Early Phase of HIV Life Cycle
(precedingEvent)	[Reaction:R-HSA-164527] Annealing of 3'-end of unwound transfer RNA primer with genomic RNA