Reactome | Binding and activation of MAP Kinase

Schema > BlackBoxEvent > Entries

authored	[InstanceEdit:188342] Nasi, Sergio, Annibali, D, 2006-10-10
catalystActivity	[CatalystActivity:171008] protein tyrosine kinase activity of p-Y419-SRC-1 [plasma membrane]
category	omitted
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:171000] Jassal, B, 2006-01-25 13:20:03
dbId	171011
displayName	Binding and activation of MAP Kinase
edited	[InstanceEdit:188340] Jassal, Bijay, 2006-10-10
eventOf	[Pathway:R-HSA-171007] p38MAPK events - Homo sapiens
followingEvent	[Reaction:R-HSA-187688] p38 MAPK phosphorylates MAPKAPK2, MAPKAPK3 - Homo sapiens
inferredFrom	[Reaction:R-RNO-187682] Binding and activation of MAP kinase - Rattus norvegicus
input	2 × [SimpleEntity:R-ALL-113592] ATP [cytosol] [Complex:R-HSA-189828] MAP kinase p38 (Mg2+ cofactor) [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Binding and activation of MAP Kinase
output	2 × [SimpleEntity:R-ALL-29370] ADP [cytosol] [Complex:R-HSA-170993] Phospho-MAP kinase p38 (Mg2+ cofactor) [cytosol]
precedingEvent	[Reaction:R-HSA-170991] SRC-1 autophosphorylates - Homo sapiens
releaseDate	2007-12-11
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:202668] Greene, LA, 2007-11-08 15:39:37
schemaClass	BlackBoxEvent
species	[Species:48887] Homo sapiens
stId	R-HSA-171011
summation	[Summation:187650] The NGF activation of p38 MAP kinase is transient, being max...

(hasEvent)	[Pathway:R-HSA-171007] p38MAPK events
(precedingEvent)	[Reaction:R-HSA-187688] p38 MAPK phosphorylates MAPKAPK2, MAPKAPK3
(inferredTo)	[Reaction:R-RNO-187682] Binding and activation of MAP kinase

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