Binding and activation of MAP Kinase

Stable Identifier
R-HSA-171011
Type
Reaction [BlackBoxEvent]
Species
Homo sapiens
Compartment
cytosol
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Binding and activation of MAP Kinase
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The NGF activation of p38 MAP kinase is transient, being maximal at 10 min and declining to near control levels by 30 min. T180 and Y182 are two sites that become newly phosphorylated as p38 MAPK becomes activated.

Participants
Input
Output
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as an event of
Catalyst Activity

protein tyrosine kinase activity of p-Y419-SRC-1 [plasma membrane]

Physical Entity
p-Y419-SRC-1 [plasma membrane] (Homo sapiens)
Activity
protein tyrosine kinase activity (GO:0004713)
Inferred From
Binding and activation of MAP kinase (Rattus norvegicus)
Authored
Nasi, S  (2006-10-10)
Annibali, D  (2006-10-10)
Reviewed
Greene, LA  (2007-11-08)
Created
Jassal, B  (2006-01-25)
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