Reactome | GCK1:GCKR complex [nucleoplasm]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:9954132] glucose sensor activity of GCK1:GCKR complex [nucleoplasm]
compartment	[Compartment:7660] nucleoplasm
consumedByEvent	[Reaction:R-HSA-170810] nucleoplasmic GCK1:GCKR complex => glucokinase (GCK1) + glucokinase regulatory protein (GCKR) - Homo sapiens
created	[InstanceEdit:170815] D'Eustachio, P, 2006-01-17 15:36:38
dbId	170804
displayName	GCK1:GCKR complex [nucleoplasm]
hasComponent	[EntityWithAccessionedSequence:R-HSA-450102] GCK [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-170805] GCKR [nucleoplasm]
inDisease	false
inferredTo	[Complex:R-MMU-170804] GCK1:GCKR complex [nucleoplasm] - Mus musculus [Complex:R-RNO-170804] GCK1:GCKR complex [nucleoplasm] - Rattus norvegicus [Complex:R-CFA-170804] GCK1:GCKR complex [nucleoplasm] - Canis familiaris [Complex:R-XTR-170804] GCK1:GCKR complex [nucleoplasm] - Xenopus tropicalis
maxDepth	2
modified	[InstanceEdit:9954133] D'Eustachio, Peter, 2025-06-06
name	GCK1:GCKR complex glucokinase:glucokinase regulatory protein complex
producedByEvent	[BlackBoxEvent:R-HSA-170796] NPC transports GCK1:GCKR from cytosol to nucleoplasm - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-170804
updateTrackers	[UpdateTracker:9869024] Update Tracker - [Complex:170804] GCK1:GKRP complex [nucleoplasm] - v32:[add_removeHasComponent, modifyName] [UpdateTracker:9964925] Update Tracker - [Complex:170804] GCK1:GCKR complex [nucleoplasm] - v94:[modifyName]

(updatedInstance)	[UpdateTracker:9869024] Update Tracker - [Complex:170804] GCK1:GKRP complex [nucleoplasm] - v32:[add_removeHasComponent, modifyName] [UpdateTracker:9964925] Update Tracker - [Complex:170804] GCK1:GCKR complex [nucleoplasm] - v94:[modifyName]
(output)	[BlackBoxEvent:R-HSA-170796] NPC transports GCK1:GCKR from cytosol to nucleoplasm
(input)	[Reaction:R-HSA-170810] nucleoplasmic GCK1:GCKR complex => glucokinase (GCK1) + glucokinase regulatory protein (GCKR)
(physicalEntity)	[CatalystActivity:9954132] glucose sensor activity of GCK1:GCKR complex [nucleoplasm]