Reactome | Virion-associated M2 protein mediated ion infusion

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Virion-associated M2 protein mediated ion infusion Show undefined attributes

catalystActivity	[CatalystActivity:189145] proton transmembrane transporter activity of Influenza A Viral Particle Docked At The Endocytic Vesicle Membrane With An Open Pore [endocytic vesicle membrane]
category	transition
compartment	[Compartment:24337] endocytic vesicle membrane [Compartment:171907] endosome lumen
created	[InstanceEdit:168327] 2007-04-16 22:35:07
crossReference	[DatabaseIdentifier:12020763] Mondo:0005812
dbId	168313
disease	[Disease:1660558] influenza
displayName	Virion-associated M2 protein mediated ion infusion
eventOf	[Pathway:R-HSA-168336] Uncoating of the Influenza Virion - Homo sapiens
followingEvent	[Reaction:R-HSA-168299] Ribonucleoprotein release from M1 proteins - Homo sapiens
goBiologicalProcess	[GO_BiologicalProcess:6576] uncoating of virus
input	[SimpleEntity:R-ALL-74722] H+ [endosome lumen] [Complex:R-FLU-189181] Influenza A Viral Particle Docked At The Endocytic Vesicle Membrane With An Open Pore [endocytic vesicle membrane]
isInDisease	true
isInferred	false
literatureReference	[LiteratureReference:169574] Ion channel activity of influenza A virus M2 protein: characterization of the amantadine block
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Virion-associated M2 protein mediated ion infusion
output	[Complex:R-FLU-189177] Acidified Influenza A Viral Particle Docked At The Endocytic Vesicle Membrane With An Open Pore [endocytic vesicle membrane]
precedingEvent	[Reaction:R-HSA-168306] Concerted hemagglutinin pore formation - Homo sapiens
relatedSpecies	[Species:9031716] Influenza A virus
releaseDate	2005-06-13
reviewStatus	[ReviewStatus:9821382] five stars
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-168313
summation	[Summation:179393] The uncoating of influenza viruses in endosomes is blocked b...
updateTrackers	[UpdateTracker:9792161] Update Tracker - [Reaction:168313] Virion-associated M2 protein mediated ion infusion - v23:[modifyText] [UpdateTracker:9792470] Update Tracker - [Reaction:168313] Virion-associated M2 protein mediated ion infusion - v20:[addLiteratureReference, modifyText]

Referrals

(updatedInstance)	[UpdateTracker:9792161] Update Tracker - [Reaction:168313] Virion-associated M2 protein mediated ion infusion - v23:[modifyText] [UpdateTracker:9792470] Update Tracker - [Reaction:168313] Virion-associated M2 protein mediated ion infusion - v20:[addLiteratureReference, modifyText]
(hasEvent)	[Pathway:R-HSA-168336] Uncoating of the Influenza Virion
(precedingEvent)	[Reaction:R-HSA-168299] Ribonucleoprotein release from M1 proteins

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