Reactome | Recognition of the Nuclear Localization Signal (NLS) by a Karyopherin Alpha Family Protein

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Recognition of the Nuclear Localization Signal (NLS) by a Karyopherin Alpha Family Protein Show undefined attributes

authored	[InstanceEdit:168269] Gillespie, ME, 2005-11-14 17:18:07
category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:168327] 2007-04-16 22:35:07
crossReference	[DatabaseIdentifier:12020763] Mondo:0005812
dbId	168297
disease	[Disease:1660558] influenza
displayName	Recognition of the Nuclear Localization Signal (NLS) by a Karyopherin Alpha Family Protein
eventOf	[Pathway:R-HSA-168271] Transport of Ribonucleoproteins into the Host Nucleus - Homo sapiens
followingEvent	[Reaction:R-HSA-168317] Recruitment of Karyopherin Beta to form a Trimeric Complex - Homo sapiens
goBiologicalProcess	[GO_BiologicalProcess:2454643] intracellular transport of virus
input	[EntityWithAccessionedSequence:R-HSA-180612] KPNA1 [cytosol] [Complex:R-FLU-188849] Ribonucleoprotein (RNP) Complex [cytosol]
isInDisease	true
isInferred	false
literatureReference	[LiteratureReference:169570] Nuclear import of influenza virus RNA can be mediated by viral nucleoprotein and transport factors required for protein import [LiteratureReference:169539] An unconventional NLS is critical for the nuclear import of the influenza A virus nucleoprotein and ribonucleoprotein
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Recognition of the Nuclear Localization Signal (NLS) by a Karyopherin Alpha Family Protein
output	[Complex:R-HSA-188871] RNP Complex:Karyopherin alpha [cytosol]
precedingEvent	[Reaction:R-HSA-168299] Ribonucleoprotein release from M1 proteins - Homo sapiens
relatedSpecies	[Species:9031716] Influenza A virus
releaseDate	2005-04-11
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:188904] Squires, B, 2006-10-29 16:42:09
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-168297
summation	[Summation:188895] The eight influenza virus genome segments never exist as nak...
updateTrackers	[UpdateTracker:9791818] Update Tracker - [Reaction:168297] Recognition of the Nuclear Localization Signal (NLS) by a Karyopherin Alpha Family Protein - v25:[add_removeInput]

Referrals

(updatedInstance)	[UpdateTracker:9791818] Update Tracker - [Reaction:168297] Recognition of the Nuclear Localization Signal (NLS) by a Karyopherin Alpha Family Protein - v25:[add_removeInput]
(hasEvent)	[Pathway:R-HSA-168271] Transport of Ribonucleoproteins into the Host Nucleus
(precedingEvent)	[Reaction:R-HSA-168317] Recruitment of Karyopherin Beta to form a Trimeric Complex

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