Reactome | Addition of nucleotides between position +11 and +30 on HIV-1 transcript

Schema > Reaction > Entries

Addition of nucleotides between position +11 and +30 on HIV-1 transcript Show undefined attributes

authored	[InstanceEdit:165064] Matthews, L, Rice, AP, 2005-07-27 00:00:00
catalystActivity	[CatalystActivity:109910] DNA-directed RNA polymerase activity of RNA Polymerase II (unphosphorylated):TFIIF complex [nucleoplasm]
category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:167126] Matthews, L, 2005-10-11 08:30:05
crossReference	[DatabaseIdentifier:12020765] Mondo:0005109
dbId	167115
disease	[Disease:1660559] Human immunodeficiency virus infectious disease
displayName	Addition of nucleotides between position +11 and +30 on HIV-1 transcript
edited	[InstanceEdit:165066] Matthews, L, 2005-07-26 23:29:22
eventOf	[Pathway:R-HSA-167162] RNA Polymerase II HIV Promoter Escape - Homo sapiens
followingEvent	[Reaction:R-HSA-167111] Extrusion of 5'-end of 30 nt long HIV-1 transcript through the pore in Pol II complex - Homo sapiens
inferredFrom	[Reaction:R-HSA-111264] Addition of nucleotides between position +11 and +30 - Homo sapiens
input	[Complex:R-HSA-167132] HIV-1 transcription complex containing 11 nucleotide long transcript [nucleoplasm] [SimpleEntity:R-ALL-9757634] NTP [nucleoplasm]
isInDisease	true
isInferred	true
literatureReference	[LiteratureReference:111265] Analysis of the open region of RNA polymerase II transcription complexes in the early phase of elongation. [LiteratureReference:111266] Promoter clearance by RNA polymerase II is an extended, multistep process strongly affected by sequence. [LiteratureReference:111267] Promoter escape by RNA polymerase II. Formation of an escape-competent transcriptional intermediate is a prerequisite for exit of polymerase from the promoter. [LiteratureReference:110389] Recycling of the general transcription factors during RNA polymerase II transcription.
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Addition of nucleotides between position +11 and +30 on HIV-1 transcript
output	[Complex:R-HSA-167120] HIV-1 transcription complex containing transcript to +30 [nucleoplasm] [SimpleEntity:R-ALL-113541] PPi [nucleoplasm]
precedingEvent	[Reaction:R-HSA-167117] Addition of nucleotides 10 and 11 on the growing HIV-1 transcript: Third Transition - Homo sapiens
relatedSpecies	[Species:164493] Human immunodeficiency virus 1
releaseDate	2006-01-23
reviewStatus	[ReviewStatus:9821382] five stars
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-167115
summation	[Summation:111268] RNA polymerase II transcription complexes are susceptible to...
updateTrackers	[UpdateTracker:9775324] Update Tracker - [Reaction:167115] Addition of nucleotides between position +11 and +30 on HIV-1 transcript - v79:[add_removeInput] [UpdateTracker:9784141] Update Tracker - [Reaction:167115] Addition of nucleotides between position +11 and +30 on HIV-1 transcript - v54:[addLiteratureReference]

Referrals

(updatedInstance)	[UpdateTracker:9775324] Update Tracker - [Reaction:167115] Addition of nucleotides between position +11 and +30 on HIV-1 transcript - v79:[add_removeInput] [UpdateTracker:9784141] Update Tracker - [Reaction:167115] Addition of nucleotides between position +11 and +30 on HIV-1 transcript - v54:[addLiteratureReference]
(precedingEvent)	[Reaction:R-HSA-167111] Extrusion of 5'-end of 30 nt long HIV-1 transcript through the pore in Pol II complex
(hasEvent)	[Pathway:R-HSA-167162] RNA Polymerase II HIV Promoter Escape
(inferredTo)	[Reaction:R-HSA-111264] Addition of nucleotides between position +11 and +30