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Schema
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Reaction
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Entries
Addition of nucleotides between position +11 and +30 on HIV-1 transcript
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authored
[InstanceEdit:165064] Matthews, L, Rice, AP, 2005-07-27 00:00:00
catalystActivity
[CatalystActivity:109910] DNA-directed 5'-3' RNA polymerase activity of RNA Polymerase II (unphosphorylated):TFIIF complex [nucleoplasm]
category
transition
compartment
[Compartment:7660] nucleoplasm
created
[InstanceEdit:167126] Matthews, L, 2005-10-11 08:30:05
dbId
167115
disease
[Disease:1660559] Human immunodeficiency virus infectious disease
displayName
Addition of nucleotides between position +11 and +30 on HIV-1 transcript
edited
[InstanceEdit:165066] Matthews, L, 2005-07-26 23:29:22
eventOf
[Pathway:R-HSA-167162] RNA Polymerase II HIV Promoter Escape - Homo sapiens
followingEvent
[Reaction:R-HSA-167111] Extrusion of 5'-end of 30 nt long HIV-1 transcript through the pore in Pol II complex - Homo sapiens
inferredFrom
[Reaction:R-HSA-111264] Addition of nucleotides between position +11 and +30 - Homo sapiens
input
[Complex:R-HSA-167132] HIV-1 transcription complex containing 11 nucleotide long transcript [nucleoplasm]
[SimpleEntity:R-ALL-9757634] NTP [nucleoplasm]
isInDisease
true
isInferred
true
literatureReference
[LiteratureReference:111265] Analysis of the open region of RNA polymerase II transcription complexes in the early phase of elongation.
[LiteratureReference:111266] Promoter clearance by RNA polymerase II is an extended, multistep process strongly affected by sequence.
[LiteratureReference:111267] Promoter escape by RNA polymerase II. Formation of an escape-competent transcriptional intermediate is a prerequisite for exit of polymerase from the promoter.
[LiteratureReference:110389] Recycling of the general transcription factors during RNA polymerase II transcription.
modified
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name
Addition of nucleotides between position +11 and +30 on HIV-1 transcript
output
[Complex:R-HSA-167120] HIV-1 transcription complex containing transcript to +30 [nucleoplasm]
[SimpleEntity:R-ALL-113541] PPi [nucleoplasm]
precedingEvent
[Reaction:R-HSA-167117] Addition of nucleotides 10 and 11 on the growing HIV-1 transcript: Third Transition - Homo sapiens
relatedSpecies
[Species:164493] Human immunodeficiency virus 1
releaseDate
2006-01-23
reviewStatus
[ReviewStatus:9821382] five stars
schemaClass
Reaction
species
[Species:48887] Homo sapiens
stId
R-HSA-167115
summation
[Summation:111268] RNA polymerase II transcription complexes are susceptible to...
Referrals
(precedingEvent)
[Reaction:R-HSA-167111] Extrusion of 5'-end of 30 nt long HIV-1 transcript through the pore in Pol II complex
(hasEvent)
[Pathway:R-HSA-167162] RNA Polymerase II HIV Promoter Escape
(inferredTo)
[Reaction:R-HSA-111264] Addition of nucleotides between position +11 and +30
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