Reactome | Integration of energy metabolism

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Integration of energy metabolism Show undefined attributes

authored	[InstanceEdit:164389] Gopinathrao, G, D'Eustachio, P, 2005-05-11 18:49:22
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:164389] Gopinathrao, G, D'Eustachio, P, 2005-05-11 18:49:22
dbId	163685
diseasePathways	[Pathway:R-HSA-5683177] Defective ABCC8 can cause hypo- and hyper-glycemias - Homo sapiens
displayName	Integration of energy metabolism
doi	10.3180/R-HSA-163685.6
eventOf	[TopLevelPathway:R-HSA-1430728] Metabolism - Homo sapiens
goBiologicalProcess	[GO_BiologicalProcess:171822] regulation of generation of precursor metabolites and energy
hasDiagram	true
hasEHLD	false
hasEvent	[Pathway:R-HSA-422356] Regulation of insulin secretion - Homo sapiens [Pathway:R-HSA-163359] Glucagon signaling in metabolic regulation - Homo sapiens [Pathway:R-HSA-163358] PKA-mediated phosphorylation of key metabolic factors - Homo sapiens [Pathway:R-HSA-163754] Insulin effects increased synthesis of Xylulose-5-Phosphate - Homo sapiens [Pathway:R-HSA-163680] AMPK inhibits chREBP transcriptional activation activity - Homo sapiens [Pathway:R-HSA-163767] PP2A-mediated dephosphorylation of key metabolic factors - Homo sapiens [Pathway:R-HSA-163765] ChREBP activates metabolic gene expression - Homo sapiens
isInDisease	false
isInferred	false
lastUpdatedDate	2023-03-29
literatureReference	[LiteratureReference:164225] A humble hexose monophosphate pathway metabolite regulates short- and long-term control of lipogenesis [LiteratureReference:164226] Glucagon and regulation of glucose metabolism [LiteratureReference:164248] The AMP-activated protein kinase pathway--new players upstream and downstream
maxDepth	5
modified	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
name	Integration of energy metabolism
orthologousEvent	[Pathway:R-MMU-163685] Integration of energy metabolism - Mus musculus [Pathway:R-RNO-163685] Integration of energy metabolism - Rattus norvegicus [Pathway:R-CFA-163685] Integration of energy metabolism - Canis familiaris [Pathway:R-BTA-163685] Integration of energy metabolism - Bos taurus [Pathway:R-SSC-163685] Integration of energy metabolism - Sus scrofa [Pathway:R-DRE-163685] Integration of energy metabolism - Danio rerio [Pathway:R-XTR-163685] Integration of energy metabolism - Xenopus tropicalis [Pathway:R-GGA-163685] Integration of energy metabolism - Gallus gallus [Pathway:R-DME-163685] Integration of energy metabolism - Drosophila melanogaster [Pathway:R-CEL-163685] Integration of energy metabolism - Caenorhabditis elegans [Pathway:R-DDI-163685] Integration of energy metabolism - Dictyostelium discoideum [Pathway:R-SPO-163685] Integration of energy metabolism - Schizosaccharomyces pombe [Pathway:R-SCE-163685] Integration of energy metabolism - Saccharomyces cerevisiae [Pathway:R-PFA-163685] Integration of energy metabolism - Plasmodium falciparum
previousReviewStatus	[ReviewStatus:9821385] four stars
releaseDate	2005-09-26
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:166645] Rush, MG, 2005-09-10 14:11:36 [InstanceEdit:9953425] Hill, David P, 2025-06-02
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-163685
summation	[Summation:164215] Many hormones that affect individual physiological processes...
updateTrackers	[UpdateTracker:9846779] Update Tracker - [Pathway:163685] Integration of energy metabolism - v84:[updateIndirectRLE] [UpdateTracker:9791014] Update Tracker - [Pathway:163685] Integration of energy metabolism - v32:[updateContainedPathway, updateIndirectRLE] [UpdateTracker:9777415] Update Tracker - [Pathway:163685] Integration of energy metabolism - v71:[updateIndirectRLE] [UpdateTracker:9784800] Update Tracker - [Pathway:163685] Integration of energy metabolism - v53:[updateIndirectRLE] [UpdateTracker:9789496] Update Tracker - [Pathway:163685] Integration of energy metabolism - v38:[updateContainedPathway] [UpdateTracker:9864262] Update Tracker - [Pathway:163685] Integration of energy metabolism - v88:[modifyText, updateContainedPathway, updateIndirectRLE] [UpdateTracker:9784470] Update Tracker - [Pathway:163685] Integration of energy metabolism - v54:[updateIndirectRLE] [UpdateTracker:9786454] Update Tracker - [Pathway:163685] Integration of energy metabolism - v49:[updateIndirectRLE] [UpdateTracker:9791648] Update Tracker - [Pathway:163685] Integration of energy metabolism - v28:[addHasEvent] [UpdateTracker:9791661] Update Tracker - [Pathway:163685] Integration of energy metabolism - v27:[updateIndirectRLE] [UpdateTracker:9774817] Update Tracker - [Pathway:163685] Integration of energy metabolism - v81:[updateContainedPathway] [UpdateTracker:9777695] Update Tracker - [Pathway:163685] Integration of energy metabolism - v69:[updateIndirectRLE] [UpdateTracker:9787711] Update Tracker - [Pathway:163685] Integration of energy metabolism - v44:[updateContainedPathway, updateIndirectRLE] [UpdateTracker:9781418] Update Tracker - [Pathway:163685] Integration of energy metabolism - v61:[updateIndirectRLE] [UpdateTracker:9911098] Update Tracker - [Pathway:163685] Integration of energy metabolism - v89:[updateIndirectRLE] [UpdateTracker:9792078] Update Tracker - [Pathway:163685] Integration of energy metabolism - v24:[addHasEvent] [UpdateTracker:9783082] Update Tracker - [Pathway:163685] Integration of energy metabolism - v57:[updateContainedPathway] [UpdateTracker:9779266] Update Tracker - [Pathway:163685] Integration of energy metabolism - v66:[modifyText] [UpdateTracker:9785161] Update Tracker - [Pathway:163685] Integration of energy metabolism - v52:[updateContainedPathway, updateIndirectRLE] [UpdateTracker:9783464] Update Tracker - [Pathway:163685] Integration of energy metabolism - v56:[updateIndirectRLE] [UpdateTracker:9792308] Update Tracker - [Pathway:163685] Integration of energy metabolism - v22:[addHasEvent, updateIndirectRLE] [UpdateTracker:9953549] Update Tracker - [Pathway:163685] Integration of energy metabolism - v93:[addHasEvent] [UpdateTracker:9846889] Update Tracker - [Pathway:163685] Integration of energy metabolism - v83:[updateIndirectRLE] [UpdateTracker:9775876] Update Tracker - [Pathway:163685] Integration of energy metabolism - v78:[updateIndirectRLE] [UpdateTracker:9775015] Update Tracker - [Pathway:163685] Integration of energy metabolism - v80:[updateIndirectRLE] [UpdateTracker:9790313] Update Tracker - [Pathway:163685] Integration of energy metabolism - v34:[updateContainedPathway] [UpdateTracker:9778593] Update Tracker - [Pathway:163685] Integration of energy metabolism - v68:[updateContainedPathway] [UpdateTracker:9789663] Update Tracker - [Pathway:163685] Integration of energy metabolism - v37:[updateIndirectRLE] [UpdateTracker:9790649] Update Tracker - [Pathway:163685] Integration of energy metabolism - v33:[add_removeHasEvent, updateContainedPathway, updateIndirectRLE]

Referrals

(hasEvent)	[TopLevelPathway:R-HSA-1430728] Metabolism
(normalPathway)	[Pathway:R-HSA-5683177] Defective ABCC8 can cause hypo- and hyper-glycemias
(updatedInstance)	[UpdateTracker:9846779] Update Tracker - [Pathway:163685] Integration of energy metabolism - v84:[updateIndirectRLE] [UpdateTracker:9791014] Update Tracker - [Pathway:163685] Integration of energy metabolism - v32:[updateContainedPathway, updateIndirectRLE] [UpdateTracker:9777415] Update Tracker - [Pathway:163685] Integration of energy metabolism - v71:[updateIndirectRLE] [UpdateTracker:9784800] Update Tracker - [Pathway:163685] Integration of energy metabolism - v53:[updateIndirectRLE] [UpdateTracker:9789496] Update Tracker - [Pathway:163685] Integration of energy metabolism - v38:[updateContainedPathway] [UpdateTracker:9864262] Update Tracker - [Pathway:163685] Integration of energy metabolism - v88:[modifyText, updateContainedPathway, updateIndirectRLE] [UpdateTracker:9784470] Update Tracker - [Pathway:163685] Integration of energy metabolism - v54:[updateIndirectRLE] [UpdateTracker:9786454] Update Tracker - [Pathway:163685] Integration of energy metabolism - v49:[updateIndirectRLE] [UpdateTracker:9791648] Update Tracker - [Pathway:163685] Integration of energy metabolism - v28:[addHasEvent] [UpdateTracker:9791661] Update Tracker - [Pathway:163685] Integration of energy metabolism - v27:[updateIndirectRLE] [UpdateTracker:9774817] Update Tracker - [Pathway:163685] Integration of energy metabolism - v81:[updateContainedPathway] [UpdateTracker:9777695] Update Tracker - [Pathway:163685] Integration of energy metabolism - v69:[updateIndirectRLE] [UpdateTracker:9787711] Update Tracker - [Pathway:163685] Integration of energy metabolism - v44:[updateContainedPathway, updateIndirectRLE] [UpdateTracker:9781418] Update Tracker - [Pathway:163685] Integration of energy metabolism - v61:[updateIndirectRLE] [UpdateTracker:9911098] Update Tracker - [Pathway:163685] Integration of energy metabolism - v89:[updateIndirectRLE] [UpdateTracker:9792078] Update Tracker - [Pathway:163685] Integration of energy metabolism - v24:[addHasEvent] [UpdateTracker:9783082] Update Tracker - [Pathway:163685] Integration of energy metabolism - v57:[updateContainedPathway] [UpdateTracker:9779266] Update Tracker - [Pathway:163685] Integration of energy metabolism - v66:[modifyText] [UpdateTracker:9785161] Update Tracker - [Pathway:163685] Integration of energy metabolism - v52:[updateContainedPathway, updateIndirectRLE] [UpdateTracker:9783464] Update Tracker - [Pathway:163685] Integration of energy metabolism - v56:[updateIndirectRLE] [UpdateTracker:9792308] Update Tracker - [Pathway:163685] Integration of energy metabolism - v22:[addHasEvent, updateIndirectRLE] [UpdateTracker:9953549] Update Tracker - [Pathway:163685] Integration of energy metabolism - v93:[addHasEvent] [UpdateTracker:9846889] Update Tracker - [Pathway:163685] Integration of energy metabolism - v83:[updateIndirectRLE] [UpdateTracker:9775876] Update Tracker - [Pathway:163685] Integration of energy metabolism - v78:[updateIndirectRLE] [UpdateTracker:9775015] Update Tracker - [Pathway:163685] Integration of energy metabolism - v80:[updateIndirectRLE] [UpdateTracker:9790313] Update Tracker - [Pathway:163685] Integration of energy metabolism - v34:[updateContainedPathway] [UpdateTracker:9778593] Update Tracker - [Pathway:163685] Integration of energy metabolism - v68:[updateContainedPathway] [UpdateTracker:9789663] Update Tracker - [Pathway:163685] Integration of energy metabolism - v37:[updateIndirectRLE] [UpdateTracker:9790649] Update Tracker - [Pathway:163685] Integration of energy metabolism - v33:[add_removeHasEvent, updateContainedPathway, updateIndirectRLE]

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