Reactome | Telomerase RNP [nucleoplasm]

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Telomerase RNP [nucleoplasm] Show undefined attributes

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-HSA-163088] Telomerase RNP:G-strand telomeric chromosome end [nucleoplasm] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-163096] Recruitment of Telomerase RNP to the Telomeric Chromosome End - Homo sapiens
created	[InstanceEdit:163097] Gillespie, ME, 2005-04-18 03:27:10
dbId	163101
displayName	Telomerase RNP [nucleoplasm]
goCellularComponent	[GO_CellularComponent:17210] telomerase holoenzyme complex
hasComponent	2 × [EntityWithAccessionedSequence:R-HSA-163102] DKC1 [nucleoplasm] 2 × [EntityWithAccessionedSequence:R-HSA-6790707] GAR1 [nucleoplasm] 2 × [EntityWithAccessionedSequence:R-HSA-418325] NHP2 [nucleoplasm] 2 × [EntityWithAccessionedSequence:R-HSA-6790665] NOP10 [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-163077] Telomerase RNA Component (TERC) [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-163076] TERT [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-418386] WRAP53 [nucleoplasm]
inDisease	false
inferredTo	[Complex:R-MMU-163101] Telomerase RNP [nucleoplasm] - Mus musculus [Complex:R-RNO-163101] Telomerase RNP [nucleoplasm] - Rattus norvegicus [Complex:R-CFA-163101] Telomerase RNP [nucleoplasm] - Canis familiaris [Complex:R-BTA-163101] Telomerase RNP [nucleoplasm] - Bos taurus [Complex:R-SSC-163101] Telomerase RNP [nucleoplasm] - Sus scrofa [Complex:R-DRE-163101] Telomerase RNP [nucleoplasm] - Danio rerio [Complex:R-XTR-163101] Telomerase RNP [nucleoplasm] - Xenopus tropicalis [Complex:R-GGA-163101] Telomerase RNP [nucleoplasm] - Gallus gallus [Complex:R-DME-163101] Telomerase RNP [nucleoplasm] - Drosophila melanogaster [Complex:R-CEL-163101] Telomerase RNP [nucleoplasm] - Caenorhabditis elegans [Complex:R-DDI-163101] Telomerase RNP [nucleoplasm] - Dictyostelium discoideum [Complex:R-SPO-163101] Telomerase RNP [nucleoplasm] - Schizosaccharomyces pombe [Complex:R-SCE-163101] Telomerase RNP [nucleoplasm] - Saccharomyces cerevisiae [Complex:R-PFA-163101] Telomerase RNP [nucleoplasm] - Plasmodium falciparum
literatureReference	[LiteratureReference:417089] Protein composition of catalytically active human telomerase from immortal cells [LiteratureReference:9667990] Cryo-EM structure of substrate-bound human telomerase holoenzyme
maxDepth	2
modified	[InstanceEdit:9983308] Weiser, Joel, 2026-02-22
name	Telomerase RNP
producedByEvent	[Reaction:R-HSA-164616] Biogenesis and assembly of the telomerase RNP - Homo sapiens [Reaction:R-HSA-163120] Disassociation of Telomerase RNP and the Chromosome End - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-163101
updateTrackers	[UpdateTracker:9868055] Update Tracker - [Complex:163101] Telomerase RNP [nucleoplasm] - v29:[addHasComponent, addLiteratureReference] [UpdateTracker:9901025] Update Tracker - [Complex:163101] Telomerase RNP [nucleoplasm] - v72:[addHasComponent, addLiteratureReference]

Referrals

(updatedInstance)	[UpdateTracker:9868055] Update Tracker - [Complex:163101] Telomerase RNP [nucleoplasm] - v29:[addHasComponent, addLiteratureReference] [UpdateTracker:9901025] Update Tracker - [Complex:163101] Telomerase RNP [nucleoplasm] - v72:[addHasComponent, addLiteratureReference]
(output)	[Reaction:R-HSA-164616] Biogenesis and assembly of the telomerase RNP [Reaction:R-HSA-163120] Disassociation of Telomerase RNP and the Chromosome End
(input)	[Reaction:R-HSA-163096] Recruitment of Telomerase RNP to the Telomeric Chromosome End
(hasComponent)	[Complex:R-HSA-163088] Telomerase RNP:G-strand telomeric chromosome end [nucleoplasm] [Complex:R-HSA-164683] Telomerase RNP Bound and base-paired to the Telomeric Chromosome End [nucleoplasm] [Complex:R-HSA-163098] Telomerase RNP:Telomeric Chromosome End with an Additional single Stranded Telomere repeat [nucleoplasm] [Complex:R-HSA-164684] Telomerase Holoenzyme Base-paired to the Telomeric Chromosome End with an Additional single Stranded Telomere repeat [nucleoplasm] [Complex:R-HSA-164619] Telomerase Holoenzyme:Telomeric RNP End with Two Additional Single Stranded Telomere Repeats [nucleoplasm]
(activeUnit)	[CatalystActivity:9668586] telomerase activity of Telomerase RNP Bound and base-paired to the Telomeric Chromosome End [nucleoplasm] [CatalystActivity:9668594] telomerase activity of Telomerase Holoenzyme Base-paired to the Telomeric Chromosome End with an Additional single Stranded Telomere repeat [nucleoplasm]

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