Reactome | Glycosaminoglycan metabolism

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Glycosaminoglycan metabolism Show undefined attributes

authored	[InstanceEdit:1630307] Jassal, B, 2011-10-05
created	[InstanceEdit:1630307] Jassal, B, 2011-10-05
dbId	1630316
displayName	Glycosaminoglycan metabolism
doi	10.3180/REACT_121315.1
edited	[InstanceEdit:1630307] Jassal, B, 2011-10-05
eventOf	[Pathway:R-HSA-71387] Metabolism of carbohydrates - Homo sapiens
goBiologicalProcess	[GO_BiologicalProcess:3777] glycosaminoglycan metabolic process
hasDiagram	true
hasEHLD	false
hasEvent	[Pathway:R-HSA-2142845] Hyaluronan metabolism - Homo sapiens [Pathway:R-HSA-174362] Transport and synthesis of PAPS - Homo sapiens [Pathway:R-HSA-1638074] Keratan sulfate/keratin metabolism - Homo sapiens [Pathway:R-HSA-1638091] Heparan sulfate/heparin (HS-GAG) metabolism - Homo sapiens [Pathway:R-HSA-1793185] Chondroitin sulfate/dermatan sulfate metabolism - Homo sapiens
isInDisease	false
isInferred	false
literatureReference	[Book:1638021] Proteoglycans and Sulfated Glycosaminoglycans [LiteratureReference:1638022] The mucopolysaccharidoses: a success of molecular medicine [LiteratureReference:1638020] The mucopolysaccharidoses: inborn errors of glycosaminoglycan catabolism
modified	[InstanceEdit:10901498] Wright, Adam, 2024-03-08
name	Glycosaminoglycan metabolism
orthologousEvent	[Pathway:R-MMU-1630316] Glycosaminoglycan metabolism - Mus musculus [Pathway:R-RNO-1630316] Glycosaminoglycan metabolism - Rattus norvegicus [Pathway:R-CFA-1630316] Glycosaminoglycan metabolism - Canis familiaris [Pathway:R-BTA-1630316] Glycosaminoglycan metabolism - Bos taurus [Pathway:R-SSC-1630316] Glycosaminoglycan metabolism - Sus scrofa [Pathway:R-DRE-1630316] Glycosaminoglycan metabolism - Danio rerio [Pathway:R-XTR-1630316] Glycosaminoglycan metabolism - Xenopus tropicalis [Pathway:R-GGA-1630316] Glycosaminoglycan metabolism - Gallus gallus [Pathway:R-DME-1630316] Glycosaminoglycan metabolism - Drosophila melanogaster [Pathway:R-CEL-1630316] Glycosaminoglycan metabolism - Caenorhabditis elegans [Pathway:R-DDI-1630316] Glycosaminoglycan metabolism - Dictyostelium discoideum [Pathway:R-SPO-1630316] Glycosaminoglycan metabolism - Schizosaccharomyces pombe [Pathway:R-SCE-1630316] Glycosaminoglycan metabolism - Saccharomyces cerevisiae
releaseDate	2012-06-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:2172129] D'Eustachio, P, 2012-03-28
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-1630316
summation	[Summation:1636575] Glycosaminoglycans (GAGs) are long, unbranched polysaccharid...

Referrals

(hasEvent)	[Pathway:R-HSA-71387] Metabolism of carbohydrates
(hasEncapsulatedEvent)	[Pathway:R-HSA-1483249] Inositol phosphate metabolism [Pathway:R-HSA-446203] Asparagine N-linked glycosylation
(normalPathway)	[Pathway:R-HSA-2206302] MPS I - Hurler syndrome [Pathway:R-HSA-2206285] MPS VI - Maroteaux-Lamy syndrome [Pathway:R-HSA-2206282] MPS IIIB - Sanfilippo syndrome B [Pathway:R-HSA-2206280] MPS IX - Natowicz syndrome [Pathway:R-HSA-2206296] MPS II - Hunter syndrome [Pathway:R-HSA-2206292] MPS VII - Sly syndrome [Pathway:R-HSA-2206308] MPS IV - Morquio syndrome B [Pathway:R-HSA-2206290] MPS IV - Morquio syndrome A [Pathway:R-HSA-2206291] MPS IIIC - Sanfilippo syndrome C [Pathway:R-HSA-3656244] Defective B4GALT1 causes B4GALT1-CDG (CDG-2d) [Pathway:R-HSA-3656243] Defective ST3GAL3 causes MCT12 and EIEE15 [Pathway:R-HSA-3560796] Defective PAPSS2 causes SEMD-PA [Pathway:R-HSA-3656253] Defective EXT1 causes exostoses 1, TRPS2 and CHDS [Pathway:R-HSA-3560792] Defective SLC26A2 causes chondrodysplasias [Pathway:R-HSA-3656248] Defective HEXB causes GM2G2 [Pathway:R-HSA-4420332] Defective B3GALT6 causes EDSP2 and SEMDJL1 [Pathway:R-HSA-3595174] Defective CHST14 causes EDS, musculocontractural type [Pathway:R-HSA-3595172] Defective CHST3 causes SEDCJD [Pathway:R-HSA-3656225] Defective CHST6 causes MCDC1 [Pathway:R-HSA-3560801] Defective B3GAT3 causes JDSSDHD [Pathway:R-HSA-3560783] Defective B4GALT7 causes EDS, progeroid type [Pathway:R-HSA-3656237] Defective EXT2 causes exostoses 2 [Pathway:R-HSA-3656234] Defective HEXA causes GM2G1 [Pathway:R-HSA-3595177] Defective CHSY1 causes TPBS [Pathway:R-HSA-2206305] MPS IIID - Sanfilippo syndrome D [Pathway:R-HSA-2206307] MPS IIIA - Sanfilippo syndrome A

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