Reactome | Inositol phosphate metabolism

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Inositol phosphate metabolism Show undefined attributes

authored	[InstanceEdit:1855226] Williams, MG, 2011-10-28
created	[InstanceEdit:1483252] Williams, MG, 2011-08-12
dbId	1483249
displayName	Inositol phosphate metabolism
doi	10.3180/R-HSA-1483249.6
edited	[InstanceEdit:1855226] Williams, MG, 2011-10-28
eventOf	[TopLevelPathway:R-HSA-1430728] Metabolism - Homo sapiens
goBiologicalProcess	[GO_BiologicalProcess:258976] inositol phosphate metabolic process
hasDiagram	true
hasEHLD	false
hasEvent	[Pathway:R-HSA-1855204] Synthesis of IP3 and IP4 in the cytosol - Homo sapiens [Pathway:R-HSA-1855196] IP3 and IP4 transport between cytosol and nucleus - Homo sapiens [Pathway:R-HSA-1855191] Synthesis of IPs in the nucleus - Homo sapiens [Pathway:R-HSA-1855170] IPs transport between nucleus and cytosol - Homo sapiens [Pathway:R-HSA-1855167] Synthesis of pyrophosphates in the cytosol - Homo sapiens [Pathway:R-HSA-1855229] IP6 and IP7 transport between cytosol and nucleus - Homo sapiens [Pathway:R-HSA-1855184] IPs transport between cytosol and ER lumen - Homo sapiens [Pathway:R-HSA-1855231] Synthesis of IPs in the ER lumen - Homo sapiens [Pathway:R-HSA-1855215] IPs transport between ER lumen and cytosol - Homo sapiens [Pathway:R-HSA-1855156] IPs transport between ER lumen and nucleus - Homo sapiens [Pathway:R-HSA-1855192] IPs transport between nucleus and ER lumen - Homo sapiens [Pathway:R-HSA-1855183] Synthesis of IP2, IP, and Ins in the cytosol - Homo sapiens
isInDisease	false
isInferred	false
lastUpdatedDate	2017-04-20
literatureReference	[LiteratureReference:1660544] Back in the water: the return of the inositol phosphates [LiteratureReference:1660552] Phosphoinositide signalling in cancer: beyond PI3K and PTEN [LiteratureReference:1660549] Inositol polyphosphates: a new frontier for regulating gene expression [LiteratureReference:1660543] Regulation of nuclear processes by inositol polyphosphates [LiteratureReference:1660550] Inositol phosphate synthesis and the nuclear processes they affect
maxDepth	3
modified	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
name	Inositol phosphate metabolism
orthologousEvent	[Pathway:R-PFA-1483249] Inositol phosphate metabolism - Plasmodium falciparum [Pathway:R-SCE-1483249] Inositol phosphate metabolism - Saccharomyces cerevisiae [Pathway:R-SPO-1483249] Inositol phosphate metabolism - Schizosaccharomyces pombe [Pathway:R-DDI-1483249] Inositol phosphate metabolism - Dictyostelium discoideum [Pathway:R-CEL-1483249] Inositol phosphate metabolism - Caenorhabditis elegans [Pathway:R-DME-1483249] Inositol phosphate metabolism - Drosophila melanogaster [Pathway:R-GGA-1483249] Inositol phosphate metabolism - Gallus gallus [Pathway:R-XTR-1483249] Inositol phosphate metabolism - Xenopus tropicalis [Pathway:R-DRE-1483249] Inositol phosphate metabolism - Danio rerio [Pathway:R-SSC-1483249] Inositol phosphate metabolism - Sus scrofa [Pathway:R-BTA-1483249] Inositol phosphate metabolism - Bos taurus [Pathway:R-CFA-1483249] Inositol phosphate metabolism - Canis familiaris [Pathway:R-RNO-1483249] Inositol phosphate metabolism - Rattus norvegicus [Pathway:R-MMU-1483249] Inositol phosphate metabolism - Mus musculus
releaseDate	2012-12-04
releaseStatus	UPDATED
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:2562610] Wundenberg, Torsten, 2012-11-06
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-1483249
summation	[Summation:2024065] Inositol phosphates (IPs) are molecules involves in signalli...
updateTrackers	[UpdateTracker:9781686] Update Tracker - [Pathway:1483249] Inositol phosphate metabolism - v60:[updateContainedPathway] [UpdateTracker:9783120] Update Tracker - [Pathway:1483249] Inositol phosphate metabolism - v57:[updateIndirectRLE] [UpdateTracker:9783712] Update Tracker - [Pathway:1483249] Inositol phosphate metabolism - v56:[updateIndirectRLE]

Referrals

(updatedInstance)	[UpdateTracker:9781686] Update Tracker - [Pathway:1483249] Inositol phosphate metabolism - v60:[updateContainedPathway] [UpdateTracker:9783120] Update Tracker - [Pathway:1483249] Inositol phosphate metabolism - v57:[updateIndirectRLE] [UpdateTracker:9783712] Update Tracker - [Pathway:1483249] Inositol phosphate metabolism - v56:[updateIndirectRLE]
(hasEvent)	[TopLevelPathway:R-HSA-1430728] Metabolism

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