Reactome | ARSC hydrolyzes steroid sulfates

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ARSC hydrolyzes steroid sulfates Show undefined attributes

authored	[InstanceEdit:1606810] Jassal, B, 2011-09-27
catalystActivity	[CatalystActivity:1606835] steryl-sulfatase activity of active STS dimer [endoplasmic reticulum membrane]
category	transition
compartment	[Compartment:12045] endoplasmic reticulum membrane [Compartment:17957] endoplasmic reticulum lumen
created	[InstanceEdit:1606810] Jassal, B, 2011-09-27
dbId	1606839
displayName	ARSC hydrolyzes steroid sulfates
edited	[InstanceEdit:1606810] Jassal, B, 2011-09-27
eventOf	[Pathway:R-HSA-196071] Metabolism of steroid hormones - Homo sapiens
input	[SimpleEntity:R-ALL-113519] H2O [endoplasmic reticulum lumen] [SimpleEntity:R-ALL-9841212] steroid sulfate [endoplasmic reticulum lumen]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:1609666] Human placental steroid sulfatase: purification and properties [LiteratureReference:1609659] Purification and properties of steroid sulfatase from human placenta [LiteratureReference:1609655] Purification and properties of arylsulfatase C from human placenta [LiteratureReference:1609652] Cloning and expression of human steroid-sulfatase. Membrane topology, glycosylation, and subcellular distribution in BHK-21 cells [LiteratureReference:1612935] Identification of point mutations in the steroid sulfatase gene of three patients with X-linked ichthyosis [LiteratureReference:1612937] Characterization of point mutations in patients with X-linked ichthyosis. Effects on the structure and function of the steroid sulfatase protein
maxDepth	1
modified	[InstanceEdit:11051501] Weiser, Joel, 2026-03-16
name	ARSC hydrolyzes steroid sulfates
orthologousEvent	[Reaction:R-SPO-1606839] ARSC hydrolyzes steroid sulfates - Schizosaccharomyces pombe [Reaction:R-GGA-1606839] ARSC hydrolyzes steroid sulfates - Gallus gallus [Reaction:R-XTR-1606839] ARSC hydrolyzes steroid sulfates - Xenopus tropicalis [Reaction:R-DRE-1606839] ARSC hydrolyzes steroid sulfates - Danio rerio [Reaction:R-SSC-1606839] ARSC hydrolyzes steroid sulfates - Sus scrofa [Reaction:R-BTA-1606839] ARSC hydrolyzes steroid sulfates - Bos taurus [Reaction:R-CFA-1606839] ARSC hydrolyzes steroid sulfates - Canis familiaris [Reaction:R-RNO-1606839] ARSC hydrolyzes steroid sulfates - Rattus norvegicus [Reaction:R-MMU-1606839] ARSC hydrolyzes steroid sulfates - Mus musculus
output	[SimpleEntity:R-ALL-1609649] SO4(2-) [endoplasmic reticulum lumen] [SimpleEntity:R-ALL-9841230] steroid [endoplasmic reticulum lumen]
releaseDate	2011-12-06
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:1863068] Stephan, Ralf, 2011-10-31
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-1606839
summation	[Summation:1606805] Steryl sulfatase (formerly arylsulfatase C, ARSC) hydrolyses...
updateTrackers	[UpdateTracker:9776491] Update Tracker - [Reaction:1606839] Steryl sulfatase hydrolyses sulfate from steroid sulfates - v75:[removeRegulator] [UpdateTracker:9842324] Update Tracker - [Reaction:1606839] ARSC hydrolyzes steroid sulfates - v86:[add_removeInput, add_removeOutput]

Referrals

(updatedInstance)	[UpdateTracker:9776491] Update Tracker - [Reaction:1606839] Steryl sulfatase hydrolyses sulfate from steroid sulfates - v75:[removeRegulator] [UpdateTracker:9842324] Update Tracker - [Reaction:1606839] ARSC hydrolyzes steroid sulfates - v86:[add_removeInput, add_removeOutput]
(hasEvent)	[Pathway:R-HSA-196071] Metabolism of steroid hormones

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