Reactome | Release of the Mature intronless transcript derived Histone mRNA:SLBP:eIF4E Complex

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Release of the Mature intronless transcript derived Histone mRNA:SLBP:eIF4E Complex Show undefined attributes

authored	[InstanceEdit:158498] Gillespie, ME, 2005-01-27 17:31:58
category	dissociation
compartment	[Compartment:70101] cytosol [Compartment:13231] nuclear envelope
created	[InstanceEdit:159049] Gillespie, ME, 2005-02-16 21:09:29
dbId	159050
displayName	Release of the Mature intronless transcript derived Histone mRNA:SLBP:eIF4E Complex
eventOf	[Pathway:R-HSA-159230] Transport of the SLBP Dependant Mature mRNA - Homo sapiens
followingEvent	[Reaction:R-HSA-72635] eIF4F binds to mRNP - Homo sapiens
goBiologicalProcess	[GO_BiologicalProcess:4519] mRNA export from nucleus
input	[EntityWithAccessionedSequence:R-HSA-72578] EIF4E [cytosol] [Complex:R-HSA-159045] Mature intronless transcript derived Histone mRNA:SLBP:TAP:Aly/Ref complex [cytosol]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:8984292] An element in the 3' untranslated region of human LINE-1 retrotransposon mRNA binds NXF1(TAP) and can function as a nuclear export element [LiteratureReference:8850630] Arginine methylation of REF/ALY promotes efficient handover of mRNA to TAP/NXF1
maxDepth	1
modified	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
name	Release of the Mature intronless transcript derived Histone mRNA:SLBP:eIF4E Complex
orthologousEvent	[Reaction:R-CEL-159050] Release of the Mature intronless transcript derived Histone mRNA:SLBP:eIF4E Complex - Caenorhabditis elegans [Reaction:R-DME-159050] Release of the Mature intronless transcript derived Histone mRNA:SLBP:eIF4E Complex - Drosophila melanogaster [Reaction:R-GGA-159050] Release of the Mature intronless transcript derived Histone mRNA:SLBP:eIF4E Complex - Gallus gallus [Reaction:R-SSC-159050] Release of the Mature intronless transcript derived Histone mRNA:SLBP:eIF4E Complex - Sus scrofa [Reaction:R-BTA-159050] Release of the Mature intronless transcript derived Histone mRNA:SLBP:eIF4E Complex - Bos taurus [Reaction:R-CFA-159050] Release of the Mature intronless transcript derived Histone mRNA:SLBP:eIF4E Complex - Canis familiaris [Reaction:R-RNO-159050] Release of the Mature intronless transcript derived Histone mRNA:SLBP:eIF4E Complex - Rattus norvegicus [Reaction:R-MMU-159050] Release of the Mature intronless transcript derived Histone mRNA:SLBP:eIF4E Complex - Mus musculus
output	[EntityWithAccessionedSequence:R-HSA-158482] ALYREF [cytosol] [Complex:R-HSA-141614] Mature intronless transcript derived Histone mRNA:SLBP:eIF4E Complex [cytosol] [EntityWithAccessionedSequence:R-HSA-156481] NXF1 [cytosol]
precedingEvent	[Reaction:R-HSA-159046] Transport of the Mature IntronlessTranscript Derived Histone mRNA:SLBP:TAP:Aly/Ref complex through the NPC - Homo sapiens
regulatedBy	[Requirement:R-HSA-159060] Requirement by 'Nuclear Pore Complex (NPC) [nuclear envelope]'
releaseDate	2005-04-11
reviewStatus	[ReviewStatus:9821382] five stars
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-159050
summation	[Summation:158502] At some point eIF4E binds the mature mRNA. While TAP and Aly...
updateTrackers	[UpdateTracker:9781036] Update Tracker - [Reaction:159050] Release of the Mature intronless transcript derived Histone mRNA:SLBP:eIF4E Complex - v61:[addLiteratureReference, modifyText]

Referrals

(updatedInstance)	[UpdateTracker:9781036] Update Tracker - [Reaction:159050] Release of the Mature intronless transcript derived Histone mRNA:SLBP:eIF4E Complex - v61:[addLiteratureReference, modifyText]
(hasEvent)	[Pathway:R-HSA-159230] Transport of the SLBP Dependant Mature mRNA
(precedingEvent)	[Reaction:R-HSA-72635] eIF4F binds to mRNP